ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2025-06-006 临床药物与手术治疗 2025, (06)

布比卡因脂质体和罗哌卡因在臂丛神经阻滞的肩关节镜手术中的镇痛效果对比

徐州医科大学附属医院

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摘要

摘要:目的 探讨在肩关节镜手术的臂丛神经阻滞中,应用布比卡因脂质体和罗哌卡因的延缓镇痛效果对比。方法 2023 年 1 月至 2024 年 12 经本院进行麻醉的肩关节镜手术患者共 82 人,按照随机分组,观察组使用布比卡因脂质体(n=42),对照组使用罗哌卡(n=40),分析两组镇痛缓解效果、药物使用情况、不良事件发生等情况。结果 两组术前疼痛评分不良事件发生率之间差异无统计学意义(P>0.05)。术后各时间段,相较于对照组,经布比卡因脂质体阻滞的观察组患者疼痛评分更低,阿片类药物累计用量更少(P<0.05)。观察组不良事件发生率低于对照组(P<0.05)。结论 在肩关节镜手术中,应用布比卡因脂质体进行臂丛神经阻滞能够有效改善术后镇痛效果,减少阿片类止痛药物用量,并降低以头晕和恶心呕吐为主的不良反应发生。

Abstract

Abstract: Objective This study aimed to investigate and compare the prolonged analgesic effects of liposomal bupivacaine and ropivacaine when applied in brachial plexus block for arthroscopic shoulder surgery. Methods A total of 82 patients who underwent arthroscopic shoulder surgery with anesthesia at our hospital from January 2023 to December 2024 were enrolled. They were randmly divided into two groups, the observation group (n=42) received liposomal bupivacaine, while the control group (n=40) was administered ropivacaine. The analgesic relief effect, drug usage, and incidence of adverse events were analyzed and compared between the two groups. Results There were no statistically significant differences in the preoperative pain scores or the incidence of adverse events between the two groups (P>0.05). At all postoperative time points, compared with the control group, the observation group (receiving liposomal bupivacaine block) had lower pain scores and a reduced cumulative consumption of opioid drugs (P<0.05). Additionally, the incidence of adverse events in the observation group was lower than that in the control group (P<0.05). Conclusion In arthroscopic shoulder surgery, the application of liposomal bupivacaine for brachial plexus block can effectively improve the postoperative analgesic effect, reduce the dosage of opioid analgesics, and decrease the occurrence of adverse reactions, mainly including dizziness, nausea, and vomiting.

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[1]田环环.布比卡因脂质体和罗哌卡因在臂丛神经阻滞的肩关节镜手术中的镇痛效果对比[J],2025,01(06):.