ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2025-04-073 检验与方法 2025, (04)

非剥脱点阵激光联合强脉冲光治疗痤疮瘢痕的效果研究

北京市第六医院

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摘要

目的 分析非剥脱点阵激光联合强脉冲光在痤疮瘢痕治疗中的具体效果。方法 研究对象为 2025 年 1月至 2025 年 5 月期间在我院接受治疗的 60 例痤疮瘢痕患者,将其随机分为两组,对照组予以强脉冲光治疗,观察组在强脉冲光治疗后,进行非剥脱点阵激光治疗,就两组的实际疗效展开分析。结果 两组治疗前和首次治疗后瘢痕严重程度评分无显著差异(P>0.05);治疗 6 个月后,观察组瘢痕严重程度评分较对照组更低(P<0.05),治疗后,观察组皮肤含水量、油脂、经皮水分丢失(TEWL)、黑素指数(MI)、红斑指数(EI)改善程度均较对照组更优,差异显著(P<0.05);观察组总有效率较对照组更高(P<0.05)。结论 非剥脱点阵激光联合强脉冲光在痤疮瘢痕治疗中效果确切,可以有效减轻患者的瘢痕严重程度,改善皮肤屏障功能。

Abstract

Objective To analyze the specific efficacy of non-ablative fractional laser combined with intense pulsed light in the treatment of acne scars. Methods The research subjects were 60 patients with acne scars who received treatment in our hospital from January 2025 to May 2025. They were randomly divided into two groups: the control group received intense pulsed light treatment, and the observation group received non-ablative fractional laser treatment after intense pulsed light treatment. The actual efficacy of the two groups was analyzed. Results There was no significant difference in scar severity scores between the two groups before and after the first treatment (P>0.05). After 6 months of treatment, the severity score of scars in the observation group was lower than that in the control group (P<0.05). After treatment, the observation group showed better improvement in skin moisture content, sebum, transdermal water loss (TEWL), melanin index (MI) and erythema index (EI) compared to the control group, with significant differences (P<0.05). The total effective rate of the observation group was higher than that of the control group (P<0.05). Conclusion The combination of non-ablative fractional laser and intense pulsed light is effective in the treatment of acne scars, effectively reducing the severity of scars in patients and improving skin barrier function.

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[1]周星,陈惠阳,刘宇超,等.非剥脱点阵激光联合强脉冲光治疗痤疮瘢痕的效果研究[J],2025,01(04):.