ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2025-04-006 中医学研究 2025, (04)

平金贴联合噻托溴铵治疗慢性阻塞性肺病急性加重期疗效观察

泸州市龙马潭区中医医院

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摘要

目的 观察平金贴联合噻托溴铵治疗慢性阻塞性肺病(COPD)急性加重期疗效。方法 采用随机对照方法将 76 例 COPD 急性加重期患者分为观察组和对照组,对照组 38 例采用常规治疗,观察组 38 例在常规治疗的基础上加贴平金贴和吸入噻托溴铵。比较两组的临床总有效率、肺功能的第一秒用力呼气容积占预计值比值(FEV1%)、氧合指数、患者生活评估测试问卷(CAT)。结果 临床总有效率观察组 92.1%,高于对照组78.9%;两组治疗后与治疗前比较,治疗后肺功能的 FEV1%、氧合指数高于治疗前、CAT 低于治疗前;观察组肺功能的 FEV1% 指标、氧合指数的指标、生活质量改善更为明显。结论 平金贴联合噻托溴铵治疗 COPD 急性加重期有较好疗效,与常规治疗联用能提高疗效。

Abstract

Objective To observe the efficacy of Pingjin Patch combined with tiotropium bromide in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods A randomized controlled method was used to divide 76 patients with acute exacerbation of COPD into an observation group and a control group, 38 cases in the control group were treated with conventional treatment, and 38 cases in the observation group received Pingjin Patch opplication and tiotropium bromide inhalation on the basis of conventional treatment. The overall clinical effectiveness, forced expiratory volume in 1 second (FEV1%) of pulmonary function, oxygenation index and the chronic obsructive pulmonary disease assessment test (CAT) were compared between the two groups. Results The total clinical effectiveness rate was 92.1% in the observation group, higher than 78.9% in the control group. When comparing the two groups after treatment with those before treatment, the FEV1% and oxygenation index of pulmonary function were higher than before treatment, and the CAT was lower than before treatment. The observation groupshowed significant improvements in FEV1%、oxygenation index and quality of life. Conclusion Pingjin Patch combined with tiotropium bromide has better efficacy in the treatment of acute exacerbation of COPD, and it can improve the efficacy when combined with conventional treatment.

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[1]王孝芳,王萍,张秋梅,等.平金贴联合噻托溴铵治疗慢性阻塞性肺病急性加重期疗效观察[J],2025,01(04):.