“益气活血、化瘀散结”中药法对子宫腺肌症高强度聚焦超声消融术后的影响

Objective To explore the effects of the “Tonifying-qi and activating-blood, resolving-stasis and dissipating-masses” traditional Chinese medicine therapy on dysmenorrhea and lesion clearance after high-intensity focused ultrasound ablation(HIFU) for uterine adenomyosis. Methods The 72 patients with uterine adenomyosis who were treated in the hospital from March 2024 to October 2025 were grouped randomly. Each group consisted of 36 patients. The control group received HIFU treatment, while the observation group received “Tonifying-qi and activatingblood, resolving-stasis and dissipating-masses” traditional Chinese medicine therapy(modified Si Junzi Decoction combined with Guizhi Fuling Decoction). The visual analogue scale(VAS), uterine volume, number of lesions, lesion volume, white blood cells(WBC), red blood cells(RBC), platelets(PLT), alanine aminotransferase(ALT), aspartate aminotransferase(AST), serum carbohydrate antigen 125(CA125), and interleukin-6(IL-6) were compared between the two groups before treatment and 3 months after treatment. Results Compared with the control group, the VAS, uterine volume, number of lesions, and lesion volume of the observation group were lower than those of the control group after treatment(P<0.05). After intervention, the observation group exhibited markedly reduced CA125 and IL-6 concentrations relative to the control cohort, with statistical significance(P<0.05). Meanwhile, post-treatment comparisons of WBC, RBC, PLT, ALT and AST indicators revealed no statistically meaningful disparities between the two groups(P>0.05). Conclusion Adding “Tonifyingqi and activating-blood, resolving-stasis and dissipating-masses” traditional Chinese medicine therapy(modified Si Junzi Decoction combined with Guizhi Fuling Decoction) after HIFU for uterine adenomyosis can further relieve dysmenorrhea, reduce the size of uterine lesions, lower lesion activity, and does not increase adverse reactions in liver function and blood system, and has additional therapeutic effects.