自拟三金补肾汤联合坦索罗辛对肾草酸钙结石患者的作用

Objective To investigate the intervention effects of self-formulated Sanjin Bu Shen Decoction combined with tamsulosin in patients with renal calcium oxalate stones. Methods A total of 70 patients with renal calcium oxalate stones admitted to the Bozhou District Hospital of Traditional Chinese Medicine, Zunyi City from February 2025 to February 2026 were enrolled and divided into two groups using a random number table method, with 35 cases in each group. The control group received tamsulosin monotherapy, while the study group received self-formulated Sanjin Bu Shen Decoction in addition to tamsulosin. The stone clearance rate, Traditional Chinese Medicine syndrome scores, frequency of renal colic episodes at different time points, and medication safety were compared between the two groups. Results The stone clearance rate at 4 weeks and 8 weeks of treatment in the study group was significantly higher than that in the control group, respectively(P<0.05). After 4 weeks of treatment, the scores of lumbosacral soreness, poor urination, difficult and painful urination, and hematuria in the study group were significantly lower than those in the control group(P<0.05). From week 1 to week 4 of treatment, the frequency of renal colic episodes per week in the study group was significantly lower than that in the control group(P<0.05). The incidence of adverse reactions was similar between the two groups(P>0.05). Conclusion Self-formulated Sanjin Bu Shen Decoction combined with tamsulosin can effectively improve the stone clearance rate, rapidly alleviate clinical symptoms, and reduce the frequency of renal colic episodes in patients with renal calcium oxalate stones, with a reliable safety profile.