ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾 疾病预防与控制 Disease Prevention and Control 医学学术期刊 月刊
2026-07-009 预防医学研究 2026, 2(07): 33-36

南京地区老年2型糖尿病患者并发糖尿病视网膜病变的流行病学特征及其影响因素分析

江苏省南京市浦口区疾病预防控制中心 2.南京医科大学第一附属医院

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摘要

目的 分析南京地区老年2型糖尿病(T2DM)患者并发糖尿病视网膜病变(DR)的流行病学特征及其影响因素。方法 采用横断面调查方法,选取2023年10月至2025年10月于本院就诊的老年T2DM患者共578例(数据来源于南京地区某三级甲等医院),根据是否合并DR分为发生组与未发生组,分析其流行病学特征,多因素Logistic回归分析DR的影响因素。结果 发生组与未发生组的性别、年龄、吸烟史、饮酒史、体重指数、糖尿病家族史、高脂血症、空腹血糖、总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、血尿酸、血肌酐对比无统计学差异(P>0.05)。两组T2DM病程、糖化血红蛋白(HbA1c)、高血压史、是否合并糖尿病周围神经病变(DPN)、是否规律用药对比,差异具有统计学意义(P<0.05)。多因素Logistic回归分析显示:T2DM病程>10年、HbA1c>7.5%、有高血压史、合并DPN、未规律用药是导致老年T2DM患者DR发生的危险因素(P<0.05)。结论 该地区老年T2DM患者DR发生风险较高,DR发病与T2DM病程>10年、HbA1c>7.5%、有高血压史、合并DPN、未规律用药密切相关。因此,临床需重点关注上述高危人群,积极采取个体化的防范对策,尽可能减少DR发生风险,确保患者身心健康。

Abstract

Objective To analyze the epidemiological characteristics and influencing factors of diabetic retinopathy(DR) in elderly patients with type 2 diabetes mellitus(T2DM) in Nanjing area. Methods A cross-sectional survey method was adopted. A total of 578 elderly patients(The data is sourced from a tertiary grade A hospital in Nanjing area). with T2DM who visited our hospital from October 2023 to October 2025 were selected. They were divided into the occurrence group and the non-occurrence group based on whether they had DR. The epidemiological characteristics were analyzed, and the influencing factors of DR were analyzed through multivariate Logistic regression. Results There were no statistically significant differences in gender, age, smoking history, drinking history, body mass index, family history of diabetes, hyperlipidemia, fasting blood glucose, total cholesterol, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, blood uric acid, and blood creatinine between the occurrence group and the non-occurrence group(P>0.05). There were statistically significant differences in the duration of T2DM, glycosylated hemoglobin(HbA1c), history of hypertension, whether diabetic peripheral neuropathy(DPN) was present, and whether regular medication was taken between the two groups(P<0.05). Multivariate Logistic regression analysis showed that a T2DM duration of more than 10 years, HbA1c level greater than 7.5%, a history of hypertension, the presence of DPN, and non-compliance with medication were risk factors for DR in elderly T2DM patients(P<0.05). Conclusion The risk of DR is relatively high among elderly T2DM patients in this area. The onset of DR is closely associated with T2DM duration over 10 years, HbA1c >7.5%, hypertension history, concomitant DPN and irregular medication. Clinically, close attention should be paid to the above high-risk populations, and individualized preventive interventions should be actively implemented to minimize the incidence of DR and protect patients' physical and mental health.

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[1]刘骏,赵中建.南京地区老年2型糖尿病患者并发糖尿病视网膜病变的流行病学特征及其影响因素分析[J].疾病预防与控制,2026,2(07):33-36.