精细化管理在区域医疗中心医院感染控制中的实践探索

Objective To explore the practical value of refined management in nosocomial infection control of pediatric regional medical centers. Methods Take a certain children's regional medical center as an example. The hospital infection monitoring data from January 2020 to December 2025 were selected. According to the management mode, they were divided into the conventional management stage(from January 2020 to December 2022) and the refined management stage(from January 2023 to December 2025). In each stage, approximately 180,000 discharged children were included(conventional stage: 180, 246, refined stage: 181,908). Basic nosocomial infection protocols were implemented in the routine management period. During the refined management period, a management system featuring hierarchical organizational management, data early warning, grid-based supervision, special project targets, and closed-loop improvement was established. Indicators including environmental hygiene monitoring outcomes, hand hygiene compliance, overall nosocomial infection incidence, surgical site infection, pathogen detection submission rate, antimicrobial medication administration, and multi-drug resistant organism prevention and control were compared between the two periods. Results The qualified rate of environmental hygiene monitoring, hand hygiene compliance rate, pathogen detection submission rate, and pre-administration pathogen test rate for restricted antimicrobials in the refined management period were significantly higher than those in the routine management period. Meanwhile, the overall nosocomial infection rate, prevalence rate, surgical site infection rate of Class I incisions, and nosocomial infection rate caused by multi-drug resistant organisms were markedly lower in the refined management period(P<0.05). Conclusion Refined management realizes visualized whole-process supervision and standardized consistent implementation of infection control in pediatric regional medical centers. It delivers positive effects on reducing infection risks in key links, promoting rational antimicrobial use, and optimizing the closed-loop quality management system.