盐酸氨溴索联合氨茶碱治疗老年慢阻肺合并肺部感染的临床效果研究

Objective To evaluate the efficacy of ambroxol hydrochloride combined with aminophylline in the treatment of elderly patients with chronic obstructive pulmonary disease(COPD) complicated by pulmonary infection.Methods A total of 46 elderly patients with COPD complicated by pulmonary infection were enrolled from January 2024 to November 2025.A double-blind method was adopted,with 23 patients assigned to the research group receiving ambroxol hydrochloride combined with aminophylline,and the remaining 23 patients assigned to the comparison group receiving aminophylline alone.The clinical efficacy,recovery status,symptom scores,inflammatory markers,and adverse reactions were compared between the two groups.Results The research group demonstrated a higher overall clinical efficacy rate than the comparison group(P<0.05).In terms of recovery,the research group showed better outcomes(P<0.05).Comparison of symptom scores between the research group and the comparison group after treatment showed superiority in the former(P<0.05).Following treatment,the research group exhibited lower levels of inflammatory factors compared to the comparison group(P<0.05).The difference in adverse reaction incidence between the two patient groups was not statistically significant(P>0.05).Conclusion The combination of ambroxol hydrochloride and aminophylline in the treatment of elderly patients with COPD complicated by pulmonary infection can improve clinical outcomes and recovery efficiency,alleviate discomfort symptoms,reduce inflammatory responses,and does not increase adverse reactions.This approach is worthy of application and promotion.