ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-04-022 临床药物与手术治疗 2026, 2(04): 85-88

经皮椎体成形术术后骨水泥分布的疗效分析及对再骨折的影响

东莞市南城医院骨科

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摘要

目的 探讨经皮椎体成形术(PVP)中骨水泥分布对骨质疏松性椎体压缩性骨折(OVCF)疗效以及对术后再骨折的影响。方法 本研究为回顾性分析,选取东莞市南城医院骨科2023年3月至2024年11月确诊并诊治的60例OVCF患者资料,根据患椎CT图像横断面骨水泥分布区域将纳入患者分为三组,分别为TL1组(n=15)、TL2组(n=24)和TL3组(n=21),各组入院后均择期行PVP术治疗。对比三组患者术前以及术后2 d、1个月、6个月、12个月的疼痛程度[视觉模拟量表(VAS)]与椎体功能[Oswestry功能障碍指数(ODI)],统计三组患者骨水泥渗漏发生率、再骨折发生率。结果 三组患者术后2 d、术后1个月、术后6个月及术后12个月的VAS评分均较术前下降,且TL3组上述各时间点的VAS评分较TL1组和TL2组低(P<0.05)。三组患者术后2 d、术后1个月、术后6个月及术后12个月的ODI评分均较术前下降,且TL3组上述各时间点的ODI评分较TL1组和TL2组低(P<0.05)。结论 PVP可有效缓解OVCF患者的疼痛并改善其功能,其疗效与骨水泥在椎体内的分布范围正相关,骨水泥弥散越充分则效果越显著。

Abstract

Objective To explore the efficacy of bone cement distribution in percutaneous vertebroplasty(PVP) on osteoporotic vertebral compression fractures(OVCF) and its influence on postoperative refracture. Methods This study was a retrospective analysis. The included subjects were the data of 60 patients diagnosed and treated with OVCF in the Department of Orthopedics of Dongguan Nancheng Hospital from March 2023 to November 2024. According to the cross-sectional bone cement distribution area of the CT images of the affected vertebrae, the included patients were divided into 3 groups. They were respectively the TL1 group(n=15), the TL2 group(n=24), and the TL3 group(n=21). After admission, all groups underwent elective PVP treatment. The pain degree [Visual Analogue Scale(VAS)] and vertebral function [Oswestry Disability Index(ODI)] of the three groups before the operation and at 2 days, 1 month, 6 months, and 12 months after the operation were compared. The incidence of bone cement leakage and refracture in the three groups was statistically analyzed. Results The VAS scores of the three groups at 2 days, 1 month, 6 months and 12 months after the operation were all lower than those before the operation, and the VAS scores of the TL3 group at each of the above time points were lower than those of the TL1 group and the TL2 group(P<0.05). The ODI scores of the three groups at 2 days, 1 month, 6 months and 12 months after the operation were all lower than those before the operation, and the ODI scores of the TL3 group at each time point were lower than those of the TL1 group and the TL2 group(P<0.05). Conclusion PVP can effectively relieve the pain of patients with OVCF and improve their function. Its therapeutic effect is positively correlated with the distribution range of bone cement in the vertebral body. The more fully the bone cement diffuses, the more significant the effect will be.

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[1]陈锐鸿,李小丽,张璐,等.经皮椎体成形术术后骨水泥分布的疗效分析及对再骨折的影响[J].疾病预防与控制,2026,2(04):85-88.