ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-03-033 临床药物与手术治疗 2026, 2(03): 129-132

右美托咪定联合高位髂筋膜阻滞对老年髋部骨折术后认知功能恢复的影响

北京积水潭医院贵州医院

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摘要

目的 探究分析右美托咪定联合高位髂筋膜阻滞对老年髋部骨折术后认知功能恢复的影响。方法 回顾性分析2022年1月至2025年6月期间,院内102例接受老年髋部骨折手术患者病历资料,其中2022年1月至2023年12月的51例患者为对照组,接受常规麻醉,2024年1月至2025年6月的51例患者为观察组,接受右美托咪定联合高位髂筋膜阻滞。对比两组临床相关指标,术后疼痛程度,应激反应状态,自控静脉镇痛使用情况以及认知功能。结果 观察组麻醉恢复室停留时间低于对照组(P<0.05)。观察组术后疼痛评分均低于对照组(P<0.05)。术后24 h观察组皮质醇及去甲肾上腺素水平低于对照组(P<0.05)。观察组术后首次按压自控静脉镇痛时间高于对照组,按压次数以及补救镇痛次数均低于对照组(P<0.05)。术后1 d、3 d、7 d观察组认知功能高于对照组(P<0.05)。结论 右美托咪定联合高位髂筋膜阻滞可更好地控制对患者认知功能所产生的影响,同时可进一步改善患者临床相关指标,术后疼痛程度,应激反应状态,自控静脉镇痛使用情况,值得推广与应用。

Abstract

Objective To explore and analyze the impact of dexmedetomidine combined with high ilioinguinal fascial plane block on cognitive function recovery after hip fracture surgery in elderly patients. Methods A retrospective analysis was conducted on the medical records of 102 elderly patients who underwent hip fracture surgery in the hospital from January 2022 to June 2025. Among them, 51 patients from January 2022 to December 2023 formed the control group and received conventional anesthesia, while 51 patients from January 2024 to June 2025 formed the observation group and received dexmedetomidine combined with high ilioinguinal fascial plane block. Clinical indicators, postoperative pain levels, stress response status, patient-controlled intravenous analgesia usage, and cognitive function were compared between the two groups. Results The stay time in the anesthesia recovery room of the observation group was shorter than that of the control group(P<0.05). The postoperative pain scores of the observation group were lower than those of the control group(P<0.05). The cortisol and norepinephrine levels in the observation group at 24 hours after surgery were lower than those in the control group(P<0.05). The time for the first self-administered intravenous analgesia after surgery in the observation group was longer than that in the control group, and the number of presses and the number of rescue analgesia times were lower than those in the control group(P<0.05). The cognitive function of the observation group was higher than that of the control group at 1 day, 3 days, and 7 days after surgery(P<0.05). Conclusion Dexmedetomidine combined with high ilioinguinal fascial plane block can better mitigate the impact on patients' cognitive function while further improving clinical indicators, postoperative pain levels, stress response status, and patient-controlled intravenous analgesia usage, making it worthy of promotion and application.

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[1]张顺梅.右美托咪定联合高位髂筋膜阻滞对老年髋部骨折术后认知功能恢复的影响[J].疾病预防与控制,2026,2(03):129-132.