严重急性呼吸道感染中肺炎支原体单一及混合感染特征

Objective To explore the epidemiological characteristics and clinical manifestations of single and mixed infections of Mycoplasma pneumoniae and other respiratory pathogens in severe acute respiratory tract infection cases in Yancheng City, and to provide a basis for early clinical diagnosis, treatment and prevention. Methods A total of 485 patients who visited tertiary hospitals in Yancheng City due to severe acute respiratory infection symptoms from January 2023 to December 2024 were selected. Mycoplasma pneumoniae and other common respiratory pathogens were detected, and the proportion of co-infection of Mycoplasma pneumoniae with other pathogens was analyzed. Compared the indicators such as the number of days of fever and the incidence of complications under different pathogen infection patterns. Results Among the 485 patients, Mycoplasma pneumoniae accounted for 11.34%. There were 400 cases(82.47%) in the single infection group and 85 cases(17.53%) in the mixed infection group. The number of days of fever and the maximum body temperature in patients with mixed infection were both higher than those in patients with single infection(P<0.05). The incidence of mixed infection complications was higher than that of the control group(P<0.05). Conclusion Among the cases of severe acute respiratory tract infections in Yancheng City, Mycoplasma pneumoniae infection is relatively common, while the mixed infection with other respiratory pathogens shows a relatively high proportion, and the clinical manifestations of patients with mixed infections are more severe.