ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-02-032 临床药物与手术治疗 2026, 2(02): 125-128

奥美拉唑联合瑞巴派特治疗慢性胃炎的有效性评估

金沙县人民医院

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摘要

目的 探究幽门螺杆菌(Hp)阴性慢性胃炎运用奥美拉唑联合瑞巴派特方案治疗的有效性。方法 选择本院2023年1月至2024年1月的90例Hp阴性慢性胃炎患者,根据随机数字表法将纳入对象分为两组,各45例。对照组患者使用注射用奥美拉唑钠,研究组在上述药物基础上使用瑞巴派特片。治疗前后,对比两组患者生活质量及临床疗效与药物不良反应。结果 治疗后,研究组患者疗效较高(P<0.05),研究组患者生活质量高于对照组(P<0.05),两组患者不良反应对比,差异无统计学意义(P>0.05),研究组患者症状积分低于对照组(P<0.05)。结论 Hp阴性慢性胃炎患者运用奥美拉唑联合瑞巴派特治疗能够提高临床疗效较高,且不会增加不良反应风险,从而可提高患者生活质量,降低临床症状积分,效果显著。

Abstract

Objective To explore the effectiveness of omeprazole combined with rebamipide regimen in the treatment of helicobacter pylori(Hp) negative chronic gastritis. Methods Ninety cases of Hp negative chronic gastritis patients were selected from our hospital from January 2023 to January 2024. The subjects were divided into two groups using the random number table method, each group of 45 cases. The control group patients used sodium omeprazole for injection, and the research group used rebaprazan tablets on the basis of the above drugs. Before and after treatment, the quality of life of the two groups was compared, and the clinical efficacy and drug reactions were compared. Results After treatment, the clinical efficacy of the research group was higher(P<0.05), the quality of life of the research group was higher than that of the control group(P<0.05), and there was no statistically significant difference in the comparison of the two groups of adverse reactions(P>0.05), the symptom score of the research group patients was lower than that of the control group(P<0.05). Conclusion Hp negative chronic gastritis patients with omeprazole combined with rebaprazan treatment can improve the clinical efficacy, and will not increase the risk of adverse reactions, thereby improving the quality of life of, reducing the clinical symptom score, and the effect is significant.

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[1]胡付勇.奥美拉唑联合瑞巴派特治疗慢性胃炎的有效性评估[J].疾病预防与控制,2026,2(02):125-128.