ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-02-031 临床药物与手术治疗 2026, 2(02): 121-124

盐酸二甲双胍缓释片+阿卡波糖治疗2型糖尿病的效果

福泉市藜山卫生院

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摘要

目的 分析2型糖尿病患者采取联用盐酸二甲双胍缓释片、阿卡波糖胶囊治疗方案的临床效果。方法于2024年1月至2025年5月福泉市藜山卫生院治疗的60例2型糖尿病患者纳入研究,分组原则为随机数字表法,两组各含30例,为对照组和观察组,治疗方案分别为对照组使用单一阿卡波糖胶囊、观察组使用盐酸二甲双胍缓释片结合阿卡波糖胶囊,比较两组患者治疗效果。结果 相比对照组临床总疗效数据,观察组更高(P<0.05);各血糖指标在治疗后均为观察组数据更低(P<0.05);观察组胰岛功能指标各项在治疗后均比对照组优(P<0.05);观察组高密度脂蛋白胆固醇在治疗后比对照组高,其他血脂指标在治疗后均比对照组低(P<0.05);两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论 利用盐酸二甲双胍缓释片和阿卡波糖胶囊结合方案治疗2型糖尿病患者,具有较高临床疗效,各指标均有良好改善,不良反应少,安全性好,临床价值显著。

Abstract

Objective To analyze the clinical effects of the combined treatment regimen of metformin hydrochloride sustained-release tablets and acarbose capsules in patients with type 2 diabetes. Methods From January 2024 to May 2025, a total of 60 patients with type 2 diabetes were included in the study at Lishan Health Center in Fuquan City. The grouping principle was the random number table method, with 30 cases in each group, including the control group and the observation group. The treatment plans was the control group used acarbose capsules alone and the observation group used metformin hydrochloride sustained-release tablets combined with acarbose capsules respectively. The therapeutic effects of the two groups were compared. Results Compared with the total clinical efficacy data of the control group, that of the observation group was higher(P<0.05). All blood glucose indicators were lower in the observation group than that in the control group after treatment(P<0.05). The islet function indicators of the observation group were all better of the control group than in the control group after treatment(P<0.05). The high-density lipoprotein cholesterol in the observation group was higher than that in the control group after treatment, and other lipid indicators were all lower than those in the control group after treatment(P<0.05). There was no difference in the incidence of adverse reactions between the two groups(P>0.05). Conclusion The combined treatment of type 2 diabetes patients with metformin hydrochloride sustained-release tablets and acarbose capsules has a high clinical efficacy. All indicators have been well improved, with few adverse reactions, good safety, and significant clinical value.

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[1]戎利梅.盐酸二甲双胍缓释片+阿卡波糖治疗2型糖尿病的效果[J].疾病预防与控制,2026,2(02):121-124.