益宫颗粒辅助治疗宫缩乏力性产后出血的临床疗效研究

Objective This study aimed to analyze the efficacy of Yigong granules in the treatment of uterine atonyinduced postpartum hemorrhage. Methods The study selected postpartum patients with uterine atony admitted to our hospital from January to June 2024 as research cases. A randomized controlled method was employed to divide the 100 enrolled patients into two groups: the control group(50 cases) and the combined group(50 cases). The control group was treated with ergometrine maleate, while the combined group received Yigong granules as an adjuvant therapy on the basis. The clinical efficacy, postpartum blood loss volume, hemostasis time, coagulation function indicators, and stress indicators were compared between the two groups. Results The total clinical efficacy rate in the combined group(92.00%) was higher than that in the control group(72.00%) with a significant difference(P<0.05). The cumulative bleeding volume at 2h, 12h, and 24h postpartum in the combined group was less than that in the control group, and the hemostasis time was shorter(P<0.05). After treatment, the prothrombin time(PT), thrombin time(TT), and activated partial thromboplastin time(APTT) in both groups decreased, and the combined group was lower than the control group(P<0.05). After treatment, the B-type natriuretic peptide(BNP), nitric oxide(NO) and nitric oxide synthase(NOS) in both groups decreased, and the combined group was lower than the control group(P<0.05). Conclusion The therapeutic effect of the Yigong granules on postpartum hemorrhage caused by uterine atony is accurate, which can improve the coagulation function of patients and reduce their stress response, and it is worthy of clinical promotion.