瑞马唑仑联合瑞芬太尼在口腔舒适化治疗中的应用及对比研究

Objective To explore the application and comparison of remimazolam combined with remifentanil in oral comfort therapy. Methods The experiment was conducted on the clinical data of 200 patients who underwent oral surgery at the Dental Treatment Center of Langzhong People's Hospital from January 2023 to December 2023. These patients were divided into a local anesthesia group(n=100, using lidocaine for local anesthesia) and a general anesthesia group(n=100, using remimazolam combined with remifentanil for intravenous infusion for sedation and analgesia) based on different anesthesia methods. The differences in intraoperative clinical indicators between the two groups were compared. Results The general anesthesia group showed significantly more stable respiratory rate(RR), heart rate, and blood pressure, with smaller fluctuations and better stability compared to the local anesthesia group(P<0.05). The frequency of pharyngeal reflex, FPS-R score, and MDAS score were all lower in the general anesthesia group than in the local anesthesia group(P<0.05). The FCS in the general anesthesia group was higher than that in the local anesthesia group(P<0.05). Conclusion Compared with lidocaine alone, remimazolam combined with remifentanil can improve patients' anxiety and fear towards dental treatment, reduce respiratory depression and sedation-related reactions. It is helpful to optimize the anesthesia plan and improve patient comfort and safety.