胰岛素抵抗及新型炎症指标与急性心梗相关进展

Abstract: Acute myocardial infarction (AMI) is a condition characterized by rapid onset, high risk, and significant mortality. The triglyceride-glucose (TyG) index, a simple and reliable surrogate marker for assessing insulin resistance, can be calculated using only fasting triglyceride and fasting blood glucose levels. This approach overcomes the limitations of the traditional hyperinsulinemic-euglycemic clamp technique, which is complex and costly, making the TyG index more suitable for widespread clinical application. The fibrinogen-to-albumin ratio (FAR), as a novel inflammatory marker, is derived from routine blood tests and integrates both coagulation and inflammatory status. Therefore, it may offer superior insights into pathophysiological changes compared to individual biochemical parameters. In recent years, growing evidence has highlighted the pivotal roles of the TyG index and FAR in AMI, not only in its pathogenesis but also in their potential to predict disease prognosis. This review aims to comprehensively summarize current research progress on the TyG index and FAR in AMI, with a focus on their value in risk assessment, thereby providing new insights and directions for clinical practice.