右美托咪定在老年下肢骨折患者手术麻醉中对血流动力学及术后认知的影响

Abstract: Objective To explore the effect of dexmedetomidine combined with bupivacaine on hemodynamic-related indicators in elderly patients with lower limb fractures. Methods A total of 66 patients over 75 years old with lower limb fractures in Lianshui County Hospital of Traditional Chinese Medicine from June 2024 to June 2025 were included. They were randomly divided into experimental group and control group, 33 cases in each group. The control group was treated with bupivacaine for spinal anesthesia while the experimental group was treated with dexmedetomidine on the basis of the control group. The differences of hemodynamics, postoperative pain and other related indicators between the two groups were compared. Results The heart rate of the experimental group was lower than of the control group, the blood oxygen saturation and cognitive function were significantly higher than those of the control group, and the postoperative pain score was lower than that of the control group. There was no significant difference in mean arterial pressure between the two groups. Conclusion Dexmedetomidine combined with bupivacaine can effectively stabilize hemodynamics, reduce postoperative pain and improve postoperative cognitive decline in elderly patients with lower limb fractures, which has certain clinical significance.