ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-01-017 临床药物与手术治疗 2026, 2(01): 125-128

老年2型糖尿病共病患者多重用药的临床观察

广州中医药大学顺德医院附属勒流医院(佛山市顺德区勒流医院)

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摘要

目的 观察老年2型糖尿病(T2DM)共病患者的多重用药情况。方法 选取2023年1月至2024年3月我院收治的198例老年T2DM共病患者作为研究对象,收集患者一般资料、诊断及用药信息,分析住院期间及出院后的多重用药(≥5种)与不当用药情况。结果 198例患者年龄为60~91岁,平均(73.45±7.54)岁;平均诊断结果数(7.83±1.53)个。降糖药物中,双胍类(67.17%)、α-糖苷酶抑制剂(46.46%)、钠-葡萄糖协同转运蛋白-2抑制剂(37.37%)和二肽基肽酶-4抑制剂(38.38%)使用率较高;降压药物以血管紧张素Ⅱ受体拮抗剂(37.37%)、β-受体阻滞剂(26.77%)和钙通道阻滞剂(25.25%)为主。依据《中国老年人潜在不适当用药判断标准(2017版)》评估,28份病历(14.14%)存在41例次不当用药。结论 老年T2DM共病患者中多重用药现象普遍,且存在不当用药风险,临床需加强用药审查与指导。

Abstract

Objective To observe the polypharmacy situation in elderly patients with comorbidities of type 2 diabetes mellitus(T2DM).Methods A total of 198 elderly patients with comorbidities of T2DM admitted to our hospital from January 2023 to March 2024 were selected as the research subjects.General data,diagnosis and medication information were collected,and the situations of multiple medications(≥5 kinds) and improper medication during hospitalization and after discharge were analyzed.Results The ages of 198 patients ranged from 60 to 91 years old(73.45±7.54 years old).The average number of diagnostic results was(7.83±1.53).Among hypoglycemic drugs,biguanides(67.17%),a-glycosidase inhibitors(46.46%),sodium-glucose cotransporter-2 inhibitors(37.37%),and dipeptidyl peptidase-4 inhibitors(38.38%) have relatively high usage rates.Antihypertensive drugs are mainly angiotensin Ⅱ receptor antagonists(37.37%),beta-blockers(26.77%),and calcium channel blockers(25.25%).According to the "Criteria for Judging Potentially Inappropriate Medication Use in Chinese Elderly People(2017 Edition)",41 cases of improper medication use were found in 28 medical records(14.14%).Conclusion Among elderly patients with comorbidities of T2DM,the phenomenon of polypharmacy is widespread,and there is a risk of improper medication.Clinically,it is necessary to strengthen the review and guidance of medication.

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[1]陈协生,伍翠璧,杨春龙,等.老年2型糖尿病共病患者多重用药的临床观察[J].疾病预防与控制,2026,2(01):125-128.