ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2025-04-019 临床药物应用 2025, (04)

中成药金振口服液联合头孢噻肟钠治疗小儿咳嗽病(痰热证)的临床研究

安徽省宁国市中医院

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摘要

目的 探讨痰热证咳嗽病患儿接受金振口服液与头孢噻肟钠联合治疗的效果。方法 选择于 2023 年4 月至 2025 年 4 月在我院就医的咳嗽病(痰热证)患儿 80 例,随机数字表法进行分组,对照组 40 例,接受头孢噻肟钠治疗,试验组 40 例,接受金振口服液联合头孢噻肟钠治疗,对比和分析症状积分、炎性指标、改善时间、治疗效果、不良反应发生率。结果 对比症状总积分,试验组治疗后低于对照组(P<0.05);对比炎性指标,试验组治疗后均低于对照组(P<0.05);对比改善时间,试验组短于对照组(P<0.05);对比治疗总有效率,试验组(97.50%)优于对照组(82.50%)(P<0.05);对比不良反应发生率,试验组(10.00%)与对照组(5.00%)差异无统计学意义(P>0.05)。结论 痰热证咳嗽病患儿接受金振口服液口服与头孢噻肟钠静滴治疗获得的效果明确,利于症状缓解、炎性指标改善,缩短症状缓解时间,且不良反应少。

Abstract

Objective To investigate the effect of the treatment in children with phlegm-heat syndrome by the combination of Jinzhen Oral Liquid and cefotaxime sodium. Methods A total of 80 children with cough (phlegm-heat syndrome) who were treated in our hospital from April 2023 to April 2025 were divided by random number table method, 40 cases in the control group were treated with cefotaxime sodium, and 40 cases in the experimental group were treated with Jinzhen Oral Liquid combined with cefotaxime sodium. The symptom scores, inflammatory indices, improvement time, therapeutic efficacy and incidence of adverse reactions were compared and analyzed. Results Compared with symptom scores, the total score of experimental group was lower than that of control group (P<0.05). Compared with the inflammatory indices, the experimental groups were lower than the control group after treatment (P<0.05). The improvement time of experimental group was shorter than that of control group (P<0.05). The total effective rate of experimental group (97.50%) was better than that of control group (82.50%) (P<0.05). The incidence of adverse reactions was compared. The difference between the experimental group (10.00%) and the control group (5.00%) was small and not statistically significant (P>0.05). Conclusion The effects achieved by children with cough due to phlegm-teat syndrome treated with oral administration of the medicine Jinzhen Oral Liquid and intravenous drip of cefotaxime sodium are definite. It is conducive to symptom relief, inflammatory index improvement, short improvement time, and less adverse reaction.

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[1]徐明春,张艳.中成药金振口服液联合头孢噻肟钠治疗小儿咳嗽病(痰热证)的临床研究[J],2025,01(04):.