吞咽造影同步咽腔测压评估帕金森病合并吞咽障碍患者特征

Objective To study the evaluation of the kinematic and biomechanical characteristics of the pharynx in patients with Parkinson's disease(PD) and swallowing disorders using manofluorography(MFG). Methods From January 2025 to March 2026, 50 patients with Parkinson's disease were selected and divided into two groups based on whether they had swallowing disorders. The control group(without dysphagia) included 23 patients, and the observation group(with dysphagia) included 27 patients. All patients underwent MFG. The pharyngeal kinematics [pressure peak at the base of the tongue, pressure peak at the lower pharynx, pressure duration, pressure rise rate, pressure peak before and after relaxation of the upper esophageal sphincter(UES), duration of UES relaxation, residual pressure of UES relaxation, and resting pressure of UES relaxation] and biomechanical parameters [hyoid bone upward displacement(HV), hyoid bone forward displacement(HA), UES opening amplitude, UES opening duration, duration of hyoid bone movement] were compared between the two groups. Results The pressure peak and pressure rise rate at the base of the tongue and the lower pharynx in the observation group were lower than those in the control group, and the pressure duration at these sites was longer in the observation group. The pressure peak before UES relaxation in the observation group was lower than that in the control group, while the pressure peak after relaxation, residual pressure, and resting pressure after relaxation were higher in the observation group, and the duration of UES relaxation was shorter in the observation group(P<0.05). The upward displacement of the hyoid bone, forward displacement of the hyoid bone, UES opening amplitude, UES opening duration, duration of hyoid bone movement in the observation group were lower than those in the control group(P<0.05). Conclusion The MFG can simultaneously capture the imaging and physiological data during the swallowing process of patients with Parkinson's disease, accurately assess the pharyngeal kinematics and biomechanical characteristics, ensure the accuracy and consistency of the data, and provide a reference for clinical diagnosis and treatment.