ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾 疾病预防与控制 Disease Prevention and Control 医学学术期刊 月刊
2026-07-005 综述 2026, 2(07): 17-20

非小细胞肺癌化疗反应与结局的放射组学预测:一项系统综述与荟萃分析

南昌大学抚州医学院 2.萍乡市人民医院 3.西安交通大学 4.杭州电子科技大学

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摘要

放射组学通过深入分析医学影像中的量化特征,能够对肿瘤类型进行客观分类,评估治疗效果,并且预测疾病的预后结局。放射组学构建的治疗反应预测模型,为临床制定个体化的医疗方案提供了关键支持。非小细胞肺癌(NSCLC)是肺癌中主要的亚型,化疗是其多学科治疗的核心组成部分。但不同患者对化疗的反应差异很大,这种显著的个体差异意味着我们迫切需要更精准的预测工具来指导治疗决策。本研究旨在系统梳理放射组学在NSCLC化疗反应以及生存结局预测领域的研究现状,全面评估相关研究的科学价值和报告质量,为NSCLC的精准化疗临床实践提供高水平的循证医学依据。

Abstract

By extracting and analyzing quantitative features from medical images, radiomics can objectively classify tumor types, assess treatment efficacy, and predict prognostic outcomes. Radiomics-based predictive models for treatment response provide critical support for personalized clinical decision-making. Non-small cell lung cancer(NSCLC) is a major subtype of lung cancer, and chemotherapy remains a core component of its multidisciplinary treatment. However, substantial interpatient heterogeneity in chemotherapy response has been observed. This marked individual variability highlights the urgent need for more precise predictive tools to guide treatment decisions. This study aims to systematically summarize the current landscape of radiomics research on predicting chemotherapy response and survival outcomes in NSCLC, comprehensively assess the scientific value and reporting quality of relevant studies, and ultimately provide highlevel evidence-based evidence to support precision chemotherapy in clinical practice for NSCLC.

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[1]方憧奕,崔甜甜,方倩,等.非小细胞肺癌化疗反应与结局的放射组学预测:一项系统综述与荟萃分析[J].疾病预防与控制,2026,2(07):17-20.