观察药物流产术后加服中药安宫生化汤的临床疗效及对炎症因子的影响

Objective To evaluate the clinical efficacy of An'gong Shenghua Decoction as an adjuvant treatment after medical abortion, focusing on its effects on abortion success rate, postoperative recovery, hormone levels, and inflammatory factors. Methods A total of 60 patients requesting medical abortion at our hospital were enrolled and randomly assigned to either an observation group or a control group by random number table method, with 30 patients per group. Both groups received standard oral mifepristone combined with misoprostol. In addition, the observation group was administered An'gong Shenghua Decoction orally 2 hours after misoprostol intake, for 7 consecutive days. The abortion success rate, postoperative recovery parameters, serum hormone levels, and inflammatory cytokine profiles in the two groups were compared. Results The abortion success rate was 93.33% in the observation group, which was significantly higher than 73.33% in the control group(P<0.05). After treatment, serum human chorionic gonadotropin(HCG) levels and interleukin-6(IL-6) concentrations were significantly lower in the observation group compared with the control group(P<0.05). Furthermore, the observation group demonstrated shorter duration of vaginal bleeding, earlier resumption of menstruation, reduced bleeding volume, and improved menstrual flow upon resumption compared with the control group(P<0.05). Conclusion Adjuvant treatment with An'gong Shenghua Decoction after medical abortion can effectively improve the success rate, reduce serum hormone levels and inflammatory cytokine production, minimize the amount and duration of vaginal bleeding, and shorten the postoperative recovery period. These findings suggest that An'gong Shenghua Decoction is a valuable adjunctive therapy worthy of wider clinical application.