ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾 疾病预防与控制 Disease Prevention and Control 医学学术期刊 月刊
2026-06-042 检验与方法 2026, 2(06): 165-168

脐动脉血气结合肺彩超对新生儿肺炎诊断价值影响的临床研究

暨南大学附属顺德医院

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摘要

目的 探究脐动脉血气联合肺彩超在新生儿感染性肺炎中的诊断应用价值。方法 选取2023年1月至2026年6月暨南大学附属顺德医院新生儿科收治的60例疑似新生儿感染性肺炎患儿,进行脐动脉血气检查与肺彩超检查。按照《新生儿感染性肺炎临床诊疗指南》(2025版)的诊断标准,将患儿分为确诊组(39例)与排除组(21例),并按脐动脉血气联合肺彩超检查结果分为阳性组(40例)与阴性组(20例)。比较各组脐动脉血气指标、炎症指标、呼吸评分及住院天数,评估联合检查的诊断效能。结果 确诊组pH、PO2、BE水平显著低于排除组,PCO2、WBC水平及入院呼吸评分、住院天数显著高于排除组(P<0.05);联合检查阳性组与阴性组的上述指标差异趋势与确诊组和排除组均一致(P<0.05)。联合诊断的灵敏度为92.31%、特异度为80.95%、阳性预测值为90.00%、阴性预测值为85.00%,约登指数为0.7326。结论 脐动脉血气联合肺彩超诊断新生儿感染性肺炎具有较高的精准度与可靠性,能有效区分患病与非患病患儿,为临床早期精准诊断提供重要依据,具备临床推广价值。

Abstract

Objective To explore the diagnostic value of umbilical artery blood gas combined with lung color Doppler ultrasound in neonatal infectious pneumonia. Methods Sixty children with suspected neonatal infectious pneumonia admitted to the Neonatology Department of Shunde Hospital Affiliated to Jinan University from January 2023 to June 2026 were selected, and all underwent umbilical artery blood gas examination and lung color Doppler ultrasound examination. According to the diagnostic criteria of the Clinical Diagnosis and Treatment Guidelines for Neonatal Infectious Pneumonia(2025 Edition), the children were divided into a confirmed group(39 cases) and an excluded group(21 cases). They were further divided into a positive group(40 cases) and a negative group(20 cases) based on the results of umbilical artery blood gas combined with lung color Doppler ultrasound. The umbilical artery blood gas indexes, inflammatory indexes, respiratory scores and length of hospital stay were compared among the groups, and the diagnostic efficacy of the combined examination was evaluated. Results The levels of pH, PO2 and BE in the confirmed group were significantly lower than those in the excluded group, while the levels of PCO2, WBC, admission respiratory score and length of hospital stay were significantly higher than those in the excluded group(P<0.05). The difference trend of the above indexes between the positive group and the negative group of the combined examination was consistent with that between the confirmed group and the excluded group(P<0.05). The sensitivity, specificity, positive predictive value, negative predictive value and Youden index of the combined diagnosis were 92.31%, 80.95%, 90.00%, 85.00% and 0.7326, respectively. Conclusion Umbilical artery blood gas combined with lung color Doppler ultrasound has high accuracy and reliability in diagnosing neonatal infectious pneumonia. It can effectively distinguish between sick and non-sick children, provide an important basis for early clinical accurate diagnosis, and is worthy of clinical promotion.

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[1]冯志荣,曾汉英,龙冠秀.脐动脉血气结合肺彩超对新生儿肺炎诊断价值影响的临床研究[J].疾病预防与控制,2026,2(06):165-168.