ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾 疾病预防与控制 Disease Prevention and Control 医学学术期刊 月刊
2026-06-043 检验与方法 2026, 2(06): 169-172

扇形束计算机断层扫描在肺癌容积旋转调强计划精准治疗中的临床应用研究

常州市肿瘤医院

0下载次数 0被引频次 1阅读次数 13参考文献
知网阅读全文
摘要

目的 探讨扇形束计算机断层扫描(FBCT)在肺癌容积旋转调强(VMAT)计划精准治疗中的临床应用效果。方法 纳入2023年10月至2025年9月在本院收治的30例患者为研究对象,其均接受VMAT放疗治疗。根据计算机断层扫描(CT)扫描定位方式不同,分成两组,即观察组和对照组,每组各15例,前者在FBCT引导下开展治疗,后者在锥形束计算机断层扫描(CBCT)引导下开展治疗,对比两组靶区定位误差、计划靶区(PTV)剂量覆盖参数、适形指数(CI)、均匀性指数(HI)及时间效率。结果 观察组在X、Y、Z三个方向的定位误差均显著低于对照组(P<0.05);观察组的D95%、D98%、V100%均显著高于对照组(P<0.05);观察组CI高于对照组,HI低于对照组(P<0.05);观察组图像扫描时长长于对照组,但总摆位时长及图像配准时长短于对照组(P<0.05)。结论 FBCT引导可显著提高肺癌VMAT计划的靶区定位精度和剂量覆盖准确性,为临床开展精准放疗方案提供重要的技术保障。

Abstract

Objective To explore the clinical application effect of fan-beam CT(FBCT) in the precise treatment of volume intensity modulated(VMAT) plan for lung cancer. Methods From October 2023 to September 2025, 30 patients in our hospital were selected as the research subjects, all of whom received VMAT. According to the CT scanning positioning methods, they were divided into two groups, namely, the observation group and the control group, with 15 cases in each group. The former was treated under the guidance of FBCT and the latter was treated under the guidance of cone-beam CT(CBCT). The target positioning error, dose coverage parameters of planned target area(PTV), conformity index(CI), uniformity index(HI) and time efficiency of the two groups were compared. Results The positioning errors of the observation group in X, Y and Z directions were significantly lower than those of the control group(P<0.05). The D95%, D98% and V100% in the observation group were significantly higher than those in the control group(P<0.05). CI in observation group was Higher than that in control group, and HI was lower than that in control group(P<0.05). The image scanning time in the observation group was longer than that in the control group, but the total setting time and image registration time were shorter than those in the control group(P<0.05). Conclusion FBCT guidance can significantly improve the target location accuracy and dose coverage accuracy of VMAT plan for lung cancer, and provide important technical support for clinical precision radiotherapy.

引用本文

按标准格式复制,或导出到文献管理软件
[1]吴文斌.扇形束计算机断层扫描在肺癌容积旋转调强计划精准治疗中的临床应用研究[J].疾病预防与控制,2026,2(06):169-172.