血必净联合抗生素治疗老年人脓毒症临床疗效分析

Objective To explore the effects of Xuebijing combined with antibiotic therapy on the hemodynamics, inflammatory immunity, and organ functions of elderly patients with sepsis. Methods A total of 80 elderly patients with sepsis treated in our hospital from January 2021 to January 2025 were selected as the research subjects. They were randomly divided into the control group(40 cases) and the observation group(40 cases) using a random number table. The control group received conventional antibiotic anti-infection and symptomatic supportive treatment, while the observation group was treated with the above-mentioned regimen in addition to Xuebijing injection. The clinical symptom recovery time, hemodynamic indicators, serum inflammatory factor levels, immune function indicators, severity of the disease, and organ function status of the two groups were compared. Results After treatment, the clinical symptom recovery time of the observation group was shorter, the changes in hemodynamic indicators were more significant, the serum inflammatory factor levels were lower, the immune function indicators were higher, and the Acute Physiology and Chronic Health Evaluation(APACHE Ⅱ) and Systemic Infection Organ Dysfunction(SOFA) scores decreased more significantly(P<0.05). Conclusion The combined use of Xuebijing and antibiotics in the treatment of elderly sepsis not only helps to stabilize the hemodynamic state of patients, but also effectively reduces inflammatory factor levels, improves immune indicators, thereby protecting organ functions. This treatment scheme is effective and safe, and is worthy of clinical promotion.