分析医院监测的出生缺陷的流行态势并提出干预对策
扬州大学医学院附属盐城妇幼保健院 2.南京医科大学附属儿童医院,江苏省儿童重大疾病研究重点实验室
目的 探究医院监测的出生缺陷的流行态势并提出干预对策。方法 选取2015-2024年期间,医院监测的449 635例围产儿数据展开研究。分析指标涵盖围产儿数、高龄产妇与低龄产妇所生围产儿占比、出生缺陷发生率及因出生缺陷导致的婴儿死亡率。同时梳理各年度出生缺陷主要类型及发生率,明确出生缺陷类型分布特征,并对比不同年份数据,深入探究出生缺陷指标变化趋势,剖析其流行态势。结果 2015-2024年,围产儿数呈下降趋势,高龄产妇所生围产儿占比逐年上升,低龄产妇所生围产儿占比较为稳定。出生缺陷发生率整体呈上升态势,从2015年3.27‰升至2024年18.85‰。出生缺陷导致的婴儿死亡下降趋势明显,各年度主要出生缺陷类型中,先天性心脏病、多指/趾发生率长期居于前列,发生率明显增长。结论 人口负增长背景下,高龄产妇比例增加与出生缺陷发生率上升存在关联,主要出生缺陷类型相对集中。应加强高龄产妇孕前与孕期管理,开展针对性出生缺陷筛查与干预,优化生育服务,降低出生缺陷发生风险及婴儿死亡率。
Objective Examine the prevalence trend of birth defects monitored in hospitals and propose intervention measures. Methods Data of 449,635 perinatal infants monitored by the hospital during the period from 2015 to 2024 were selected for the study. The analysis indicators covered the number of perinatal infants, the proportion of perinatal infants born to elderly and young parturients, the incidence of birth defects, and the infant mortality rate caused by birth defects. At the same time, sorted out the main types and incidence rates of birth defects in each year, clarified the distribution characteristics of birth defect types, and compared the data of different years to deeply explore the changing trends of birth defect indicators and analyze their prevalence trend. Results From 2015 to 2024, the number of perinatal infants showed a downward trend. The proportion of perinatal infants born to elderly parturients increased year by year, while the proportion of perinatal infants born to younger parturients remained relatively stable. The incidence of birth defects has generally been on the rise, increasing from 3.27 per thousand in 2015 to 18.85 per thousand in 2024. The number of infant deaths caused by birth defects has shown a significant downward trend. Among the major types of birth defects in each year, the incidence of congenital heart disease and polydactyly has long been at the forefront, with a marked increase in incidence. Conclusion Against the backdrop of negative population growth, the increase in the proportion of elderly parturients is associated with the rising incidence of birth defects, and the main types of birth defects are relatively concentrated. It is necessary to strengthen the pre-pregnancy and pregnancy management of elderly pregnant women, carry out targeted screening and intervention for birth defects, optimize fertility services, reduce the risk of birth defects, and lower the infant mortality rate.
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| 文章编号 | 2026-05-011(期号内编号) |
|---|---|
| 栏目 | 预防医学研究 |
| 作者 | 陈春晓1;路长贵2;郑文1;肖婷1;易亮1;王素杰1 |
| 作者单位 | 扬州大学医学院附属盐城妇幼保健院 2.南京医科大学附属儿童医院,江苏省儿童重大疾病研究重点实验室 |
| 基金项目 | 江苏省儿童早期发展与慢病防治重点实验室开放课题,人口负增长背景下基于医院监测的盐城市出生缺陷流行现状及综合防治对策研究(YLT2024015) |
| 中图分类号 | R174 |
| 卷期页码 | 2026, 2(05): 41-44 |
| 发布时间 | 2026-08-15 |
| 出版时间 | 2026-08-15 |
| 引用信息 | [1]陈春晓,路长贵,郑文,等.分析医院监测的出生缺陷的流行态势并提出干预对策[J].疾病预防与控制,2026,2(05):41-44. |
| 全文地址 | 在知网查看该文(kns.cnki.net) |
| 数据抓取时间 | 2026-09-22T12:07:41 |