高敏心肌肌钙蛋白T与ST段抬高型心肌梗死冠脉病变严重程度的相关性研究

Objective To explore the correlation between hs-cTnT and the severity of coronary artery lesions in STEMI patients. Methods A total of 87 patients who underwent percutaneous coronary intervention(PCI) in the Department of Cardiology of Houjie Hospital in Dongguan City from November 2024 to July 2025 were selected as the observation group. Meanwhile, 87 patients with normal coronary angiography results were chosen as the control group. The highest values of high-sensitivity cardiac troponin T(hs-cTnT), white blood cells, liver and kidney functions, and other indicators within the first three days of hospitalization were compared between the two groups. The observation group was further divided into a mild lesion group(33 cases), a moderate lesion group(26 cases), and a severe lesion group(28 cases) based on the degree of coronary artery lesions, and the hs-cTnT, white blood cells, liver and kidney functions, and other indicators were compared with those of the 87 patients in the control group. Results The levels of white blood cells, alanine aminotransferase, N-terminal pro-brain natriuretic peptide(NT-proBNP), creatinine, uric acid, and hs-cTnT in the observation group were significantly higher than those in the control group, and this difference was statistically significant(P<0.05). Further analysis revealed that only the hs-cTnT level was associated with the severity of coronary lesions. The hs-cTnT level in the mild lesion group was significantly lower than that in the moderate and severe lesion groups, and the difference was statistically significant(P<0.05). The concentration of hs-cTnT in the moderate lesion group was also lower than that in the moderate lesion group, and this difference was statistically significant(P<0.05). Correlation analysis indicated that the hs-cTnT level in STEMI patients was positively correlated with coronary artery lesions(r=0.610, P<0.05). Conclusion Serum hs-cTnT level is positively correlated with the severity of coronary artery lesions in STEMI patients. It may serve as a potential noninvasive serological marker for assessing coronary complexity.