泌尿系结石的代谢评估与复发预防策略研究

Objective To explore the application value of individualized prevention strategies based on systemic metabolic indicators in reducing recurrence among patients with initial urolithiasis. Methods From January 2024 to January 2025, 120 hospitalized surgical patients were selected and randomly divided into the intervention and the control groups, with 60 cases in each group. The control group received general health education, while the intervention group underwent monitoring of systemic metabolic indicators(24-hour urine samples and blood biochemistry) and received individualized prevention(dietary adjustment, drug intervention, etc) according to the evaluation results. After 12 months, changes in stone recurrence rate, metabolic indicators, and SF-36 scores were observed. Results The recurrence rate of the intervention group was 8.6%(5/58), which was significantly lower than 25.4%(15/59) of the control group(P<0.05). The levels of 24-hour urine calcium, urine oxalic acid, urine uric acid, urine sodium and blood uric acid in the intervention group were decreased, and the level of urine citric acid was increased(P<0.05), and the improvement was significantly better than that in the control group(P<0.05). In terms of quality of life, the scores of role physical(PF), role physical(RP), general health(GH), vitality(VT) and mental health(MH) in the intervention group were higher(P<0.05). Conclusion For patients with initial urolithiasis, individualized prevention based on metabolic evaluation can correct metabolic abnormalities, reduce short-term recurrence, and improve quality of life.