ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-02-060 护理学研究 2026, 2(02): 237-240

循证护理下重症监护室脓毒症患者液体复苏护理的优化研究

上海市电力医院

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摘要

目的 优化基于循证护理的重症监护室(ICU)脓毒症患者液体复苏护理方案,为ICU脓毒症患者液体复苏护理实践提供科学依据。方法 选取2023年3月至2024年9月我院ICU收治的脓毒症患者160例,采用随机数字表法将其分为观察组与对照组,每组80例。对照组实施常规液体复苏护理方案,观察组实施基于循证护理优化后的液体复苏护理方案。比较两组患者的液体复苏相关指标、血流动力学指标及器官功能指标。结果观察组复苏液体总量显著少于对照组,1小时复苏达标率显著高于对照组,差异有统计学意义(P<0.001)。复苏1小时后,观察组平均动脉压、中心静脉压、乳酸清除率显著优于对照组,差异有统计学意义(P<0.001)。护理7天后,观察组急性生理学与慢性健康状况评分Ⅱ(APACHEⅡ)、血肌酐、总胆红素显著低于对照组,差异有统计学意义(P<0.001)。结论 基于循证护理的脓毒症患者液体复苏方案,可减少复苏液体总量、提升1小时达标率,还能改善平均动脉压等血流动力学指标,减轻器官功能损伤。该方案克服常规护理盲目性,为ICU脓毒症护理提供标准化循证模式,尤其适用于脓毒性休克患者,具备临床推广价值。

Abstract

Objective To optimize the fluid resuscitation care plan for sepsis patients in the intensive care unit(ICU) based on evidence-based nursing, providing a scientific basis for fluid resuscitation practice in ICU sepsis patients. Methods From March 2023 to September 2024, 160 sepsis patients admitted to our ICU were selected and randomly divided into an observation group and a control group by random number table, with 80 cases in each group. The control group received routine fluid resuscitation care, while the observation group received an optimized fluid resuscitation care plan based on evidence-based nursing. Fluid resuscitation-related indexes, hemodynamic parameters, and organ function indicators were compared between the two groups of patients. Results The total amount of resuscitation fluid in the observation group was significantly less than that in the control group and the 1-hour resuscitation rate was significantly higher than that of the control group, with statistically significant differences(P<0.001). After 1 hours of resuscitation, the observation group showed better mean arterial pressure, central venous pressure, and lactate clearance rate compared to the control group, with statistically significant differences(P<0.001). After 7 days of care, the observation group had significantly lower Acute Physiology and Chronic Health Evaluation II(APACHE II) scores, serum creatinine, and total bilirubin than the control group, with statistically significant differences(P<0.001). Conclusion An evidence-based nursing fluid resuscitation plan for sepsis patients can reduce the total volume of resuscitation fluids, increase the 1-hour resuscitation achievement rate, improve hemodynamic parameters such as mean arterial pressure, and mitigate organ injury. This plan addresses the blind spots of routine care, provides a standardized evidence-based model for ICU sepsis care, and is especially suitable for patients with septic shock, with clinical promotion value.

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[1]刘文元.循证护理下重症监护室脓毒症患者液体复苏护理的优化研究[J].疾病预防与控制,2026,2(02):237-240.