ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-01-061 检验与方法 2026, (01)

引导骨再生术联合颌骨囊肿刮治术治疗牙源性颌骨囊肿的效果分析

江苏大学附属医院

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摘要

摘要:目的 探究引导骨再生术(GBR)联合颌骨囊肿刮治术在牙源性颌骨囊肿患者临床治疗中的效果。方 法 按照随机双色球法对 2022 年 1 月至 2024 年 11 月本院收治的牙源性颌骨囊肿患者 100 例进行分组,对照组 (50 例)实施颌骨囊肿刮治术,研究组(50 例)实施引导骨再生术联合颌骨囊肿刮治术,对比两组患者临床效 果。结果 研究组术后 6 个月的临床疗效高于对照组(P<0.05),研究组术后 3 个月和术后 6 个月的上 / 下颌骨高度、颌骨宽度、咀嚼效率、咬合力均高于对照组(P<0.05),研究组术后 7 d 的疼痛指数(VAS)评分低于对照组(P<0.05),术后 6 个月内研究组疾病复发率低于对照组(P<0.05),研究组术后 7 d 的龈沟液分泌量(GCF)和 C 反应蛋白(CRP)、白介素 -6(IL-6)水平均低于对照组(P<0.05)。结论 在牙源性颌骨囊肿的临床治疗中,引导骨再生术和颌骨囊肿刮治术的联合应用能够有效促进颌骨修复,提高患者咀嚼功能,减少病症复发。

Abstract

Abstract: Objective To explore the effect of guided bone regeneration (GBR) combined with curettage of jaw cyst in the clinical treatment of patients with odontogenic jaw cysts. Methods According to the random double chromosphere method, 100 patients with odontogenic maxillary cysts admitted to our hospital from January 2022 to November 2024 were divided into two groups: the control group (50 cases) underwent curettage of jaw cyst, while the research group (50 cases) underwent guided bone regeneration combined with curettage of jaw cyst. The clinical effects of the two groups were compared. Results At 6 months postoperatively, the clinical efficacy in the research group was significantly higher than those in the control group (P<0.05). The maxillary/mandibular height, mandibular width, masticatory efficiency, and occlusal force in the research group were also significantly higher than those in the control group at both 3 and 6 months postoperatively (P<0.05). The pain index (VAS) score in the research group was significantly lower than that in the control group at 7 days postoperatively (P<0.05). The disease recurrence rate within 6 months postoperatively was lower in the research group than in the control group (P<0.05). Additionally, the gingival crevicular fluid secretion (GCF), C-reactive protein (CRP), and interleukin-6 (IL-6) levels in the research group were significantly lower than those in the control group at 7 days postoperatively (P<0.05). Conclusion In the clinical treatment of odontogenic jaw cysts, the combined application of guided bone regeneration surgery and curettage of jaw cyst can effectively promote jawbone repair, effectively improve patient chewing function, and reduce disease recurrence.

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[1]黄育萌,李梦琦,陈雨妍,等.引导骨再生术联合颌骨囊肿刮治术治疗牙源性颌骨囊肿的效果分析[J],2026,01(01):.