2014-2024年山东省德州市流感流行特征及病原学分析

Objective To understand influenza epidemiological characteristics and etiological surveillance results in Dezhou from 2014 to 2024,and provide reference for local prevention and control strategy adjustment.Methods Epidemiological analysis of influenza-like case(ILI) and etiological detection data from 3 influenza sentinel hospitals and Dezhou Center for Disease Control and Prevention influenza network laboratory.Results A total of 34,746 ILI cases were reported,ILI%=1.34%,with significant annual differences(χ2=103.146,P<0.001) and peak 8.41% in 2023-2024.High incidence was in winter-spring(October-March),positivity rate over 20% in December-January,and 5,129 peak cases in October 2023-2024.Age-wise,0～4 and 25～59 years old accounted for over 26.00% each;5～14 years old had the highest positivity rate(19.52%),≥60 years old the lowest(2.78%),with significant differences(P <0.001).Etiological surveillance shows 3,024 positive among 34,746 specimens(positivity rate 8.70%).Influenza A H3N2 was the main strain(1,279 cases),followed by B/BV(794 cases),accounting for 61.36% in 2023-2024.No significant gender difference(χ2=9.767,P=0.082).Conclusion Dezhou has obvious annual influenza epidemic differences,with winter-spring as high-incidence period.5～14 years old is the key prevention group.Influenza A H3N2 and B/BV are main strains,supporting local strategy optimization.