抗结核板式药物治疗肺结核的效果及不良反应情况探讨
资兴市疾病预防控制中心
摘要:目的 探究肺结核治疗期间应用抗结核板式药物的治疗效果。方法 将本院在 2020 年 1 月至 2024 年 12 月收治肺结核患者作为研究对象,共 500 例,按照随机数字表法分成两组,对照组(n=250)给予标准化抗结核治疗方案,观察组(n=250)则实施抗结核板式药物治疗,分析两组患者治疗效果。结果 观察组临床治愈率达到 96.00%,显著高于对照组的 91.20%(P<0.05);治疗依从性评估显示观察组配合度优于对照组(P<0.05); 观察组患者服药后不良反应发生率较高(P<0.05);但在痰菌转阴、影像学病灶吸收及空洞闭合等关键指标方面,观察组改善程度高于对照组(P<0.05)。结论 在结核病的临床药物治疗中,抗结核板式药物的应用显示出良好的治疗效果,其在提升治疗依从性、简化用药方案方面具有明确优势,有助于优化治疗管理并改善患者预后。
Abstract: Objective To explore the therapeutic effect of anti-tuberculosis tablet-based medication during the treatment of tuberculosis. Methods 500 patients with pulmonary tuberculosis admitted to our hospital from January 2020 to December 2024 were selected as the research subjects. They were randomly divided into two groups using a random number table method, the control group (n=250) received standardized anti tuberculosis treatment regimen, while the observation group (n=250) received anti tuberculosis tablet-based medication treatment. The treatment effects of the two groups were analyzed. Results The clinical cure rate of the observation group reached 96.00%, significantly higher than the control group’s 91.20% (P<0.05). The evaluation of treatment compliance showed that the compliance of the observation group was better than that of the control group (P<0.05). The incidence of adverse reactions in the observation group was higher after taking medication (P<0.05). However, in terms of key indicators such as sputum conversion to negative, absorption of imaging lesions, and closure of cavities, the observation group showed a higher degree of improvement than the control group (P<0.05). Conclusion In the clinical drug treatment of tuberculosis, the application of anti tuberculosis tablet-based medication has shown good therapeutic effects. It has clear advantages in improving treatment compliance and simplifying drug use schemes, which is helpful to optimize treatment management and improve patient prognosis.
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共 0 条| 文章编号 | 2026-01-027(期号内编号) |
|---|---|
| 栏目 | 预防医学研究 |
| 作者 | 严荣华;沈艳平;李倩玺 |
| 作者单位 | 资兴市疾病预防控制中心 |
| 卷期页码 | 2026, (01) |
| 发布时间 | - |
| 出版时间 | - |
| 引用信息 | [1]严荣华,沈艳平,李倩玺.抗结核板式药物治疗肺结核的效果及不良反应情况探讨[J],2026,01(01):. |
| 全文地址 | 在知网查看该文(kns.cnki.net) |
| 数据抓取时间 | 2026-09-22T12:25:09 |