ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-01-022 中医学研究 2026, (01)

十宣放血联合加味柴胡加龙骨牡蛎汤治疗癫痫的临床观察

潍坊市中医院

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摘要

摘要:目的 探讨在少阳枢机理论指导下,应用十宣放血联合加味柴胡加龙骨牡蛎汤治疗癫痫患者的临床疗效。方法 选取 2023 年 1 月至 2025 年 4 月收治的 84 例癫痫患者参与研究,随机分配为对照组(42 例)与观察组(42 例)。对照组给予常规西药(丙戊酸钠)治疗,治疗组在对照组的基础上用加味柴胡加龙骨牡蛎汤、十宣放血治疗,比较两组患者治疗后癫痫发作频率、发作持续时间、发作严重程度、脑电图(EEG)、生活质量的改变情况。结果 治疗后,观察组癫痫发作频次和发作持续时间改善情况优于对照组(P<0.05),癫痫发作严重程度量表(NHS3)评分显著低于对照组(P<0.05),而生活质量评定量表(QOLIE-31)评分及 EEG 等客观指标的改善程度则显著优于对照组(P<0.05)。结论 基于少阳主枢理论,十宣放血联合加味柴胡加龙骨牡蛎汤治疗癫痫患者,可降低癫痫发作严重程度,减少脑电图异常放电,提升癫痫患者生活质量。

Abstract

Abstract: Objective To investigate the clinical efficacy of Shixuan bloodletting combined with Modified Chaihu Jia Longgu Muli Decoction in treating epilepsy patients under the guidance of the Shaoyang Pivotal Mechanism theory. Methods A total of 84 epilepsy patients admitted from January 2023 to April 2025 were enrolled in the research and randomly assigned to either a control group (n=42) and an observation group (n=42). The control group received conventional western medicine (sodium valproate) treatment, while the observation group received modified Chaihu Jia Longgu Muli Decoction and pricking bloodletting therapy at the ShiXuan in addition to the control treatment. Compared the changes in the frequency of epileptic seizures, duration of seizures, severity of seizures, electroenlephatogram (EEG), and quality of life of the two groups of patients after treatment. Results After treatment, the observation group demonstrated significantly lower scores on the National Hospital Seizure Severity Scale (NHS3) compared to the control group (P<0.05). Moreover, the observation group showed significantly greater improvements in Quality of Life in Epilepsy-31 (QOLIE-31) scores and objective EEG parameters (P<0.05). Conclusion Guided by the theory of Shaoyang as the pivot, the combined therapy of pricking bloodletting at the ten fingertips and Modified Chaihu Jia Longgu Muli Decoction resulted in reduced seizure severity, decreased abnormal EEG discharges, and improved quality of life.

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[1]王向雷,杨晓云.十宣放血联合加味柴胡加龙骨牡蛎汤治疗癫痫的临床观察[J],2026,01(01):.