宫腔镜治疗子宫内膜增生症的疗效与安全性分析

Abstract: Objective To investigate the clinical efficacy of hysteroscopy treatment in patients with endometrial hyperplasia (EH) and evaluate the safety of the protocol. Methods A total of 82 EH patients admitted to our hospital from December 2023 to December 2024 were randomly divided into two groups according to different treatment methods: a control group and an observation group, with 41 cases in each group. The control group was treated with conventional oral progesterone drugs, while the observation group was treated with lesion removal under hysteroscopy. After 1 year of treatment, the patients were followed up, and the safety of different regimens was evaluated based on the differences in pathological remission rate, symptom remission rate, pregnancy outcome, and safety indicators between the two groups. Results The pathological remission rate of the observation group was higher than that of the control group, the symptom remission rate was higher than that of the control group, the recurrence rate within one year after treatment was lower than that of the control group, the natural pregnancy rate was higher than that of the control group, the live birth rate was higher than that of the control group, the pathological remission time was shorter than that of the control group, and the incidence of postoperative complications in the observation group was relatively lower. The incidence of drug side effects in the control group was higher , with statistically significant differences (P＜0.05). Before treatment, there was no statistically significant difference in endometrial thickness, progesterone, and estradiol indicators between the two groups (P＞0.05). After treatment, the endometrial thickness and estradiol levels in the observation group were lower than those in the control group, while progesterone levels were higher than those in the control group, with statistically significant differences (P＜0.05). Conclusion Hysteroscopy treatment for EH has achieved significant results. This plan has the advantages of short treatment cycle and low incidence of postoperative complications. It can effectively promote pathological and symptom relief, improve pregnancy outcomes and reduce the risk of recurrence, optimize indicators such as endometrial thickness. It is more suitable for patients with fertility needs or poor drug treatment effects in clinical practice.