ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2025-05-065 检验与方法 2025, (05)

无症状人群胃肠镜筛查在消化道肿瘤早诊中的临床研究

东莞市长安医院

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摘要

摘要:目的 本研究旨在分析总结胃肠镜筛查在无症状人群消化道肿瘤早诊中的临床价值。方法 研究通过 分析 2024 年 6 月至 2024 年 10 月本地区 1 000 例无症状中老年人群胃肠镜筛查数据,评估消化道息肉及肿瘤性 病变的检出特征。结果 共完成胃镜检查 1 000 例、肠镜检查 994 例。萎缩性胃炎伴 / 不伴肠化检出率为 9.0% (90/1 000),胃息肉检出率为 31.0%(310/1 000),结直肠息肉检出率为 56.14%(558/994)。病理结果分析结果显 示,胃底腺息肉占胃息肉绝大多数,而结直肠腺瘤占比 15.90%(158/994);早期癌 / 高级别上皮内瘤变检出率 为 0.5%(5/1 000),进展期癌 0.4%(4/1 000)。癌前病变检出率随着年龄的增长呈上升趋势,且男性高于女性,差异均有统计学意义(P<0.05)。结论 胃肠镜筛查筛查诊断能有效识别中老年人群消化道癌前病变及早期肿瘤,对消化道肿瘤的二级预防具有显著价值。

Abstract

Abstract: Objective To summarize and analyze the clinical value of gastrointestinal endoscopy in the early diagnosis of digestive tract tumors in asymptomatic populations. Methods The study analyzed screening data from 1,000 asymptomatic middle-aged and elderly individuals in the region from June 2024 to October 2024, evaluating the detection characteristics of digestive tract polyps and neoplastic lesions. Results A total of 1,000 gastroscopies and 994 colonoscopies were completed. The detection rates were as follows: atrophic gastritis with/without intestinal metaplasia 9.0% (90/1,000). gastric polyps 31.0% (310/1,000). and colorectal polyps 56.14% (558/994). Pathological analysis revealed that fundic gland polyps accounted for the majority of gastric polyps, while colorectal adenomas constituted 15.90% (158/994). The detection rates of early cancer/high-grade intraepithelial neoplasia and advanced cancer were 0.5% (5/1,000) and 0.4% (4/1,000), respectively. The detection rate of precancerous lesions increased with age and was higher in males than in females, with statistically significant differences (P<0.05). Conclusion Gastrointestinal endoscopy can effectively identify precancerous lesions and early-stage tumors in middle-aged and elderly populations, demonstrating significant value in the secondary prevention of digestive tract tumors.

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[1]陈泽森.无症状人群胃肠镜筛查在消化道肿瘤早诊中的临床研究[J],2025,01(05):.