免疫组化技术在制作病理组织切片中的应用效果分析

Abstract: Objective To explore the impact of immunohistochemical technology on the section preparation effect and disease diagnosis rate in the production of pathological tissue sections. Methods A total of 80 pathological tissue specimens from the Pathology Department of Yunfu People’s Hospital between January 2024 and December 2024 were selected as the research objects. According to the different methods of making pathological tissue sections, the samples were divided into a control group and an observation group, with 40 cases in each group. The control group adopted conventional technology, while the observation group used immunohistochemical technology. The section preparation effect, disease diagnosis rate, intact preservation rate of tissue antigens, and section preparation time were compared between the two groups. Results The excellent and good rate of section effect in the observation group was higher than that in the control group (P＜0.05). Pathological diagnosis was performed in both groups. The positive detection rate of diseases in the observation group was higher than that in the control group, and the missed diagnosis rate was lower than that in the control group (P＜0.05). After evaluation, the intact tissue antigen preservation rate in the sections of the observation group was higher, and the overall sectioning time was significantly shorter than that in the control group (P＜0.05). Conclusion The application of immunohistochemical technology in the preparation of pathological tissue sections can achieve excellent section quality, thereby improving the disease diagnosis rate and optimizing the effect of pathological diagnosis.