ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾 疾病预防与控制 Disease Prevention and Control 医学学术期刊 月刊
2026-06-049 检验与方法 2026, 2(06): 193-196

尿干化学与尿沉渣联合检测在泌尿系统疾病筛查中的临床价值分析

山西盈康一生总医院

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摘要

目的 探究尿干化学联合尿沉渣检测在泌尿系统疾病筛查中的临床应用价值,对比单一检测与联合检测的诊断效能差异,为泌尿系统疾病快速、精准筛查提供临床依据。方法 采用回顾性研究方法,筛选2024年1月至2025年6月期间我院肾病科和泌尿科收治的200例疑似泌尿系统疾病患者作为研究对象,所有研究对象均同期完成尿干化学、尿沉渣两项检测,统计尿干化学检测、尿沉渣检测、联合检测结果。同时以临床综合诊断及6个月随访结局为金标准,比较3种检测方式的诊断效能。结果 联合检测的诊断灵敏度、准确度效能指标均高于两种单一检测方法,差异有统计学意义(P<0.05);联合检测的特异度虽略有下降,但与单一检测相比差异无统计学意义(P>0.05)。尿干化学与尿沉渣检测一致性处于中等程度(kappa=0.58)。结论 临床整合尿干化学快速筛查、尿沉渣有形成分精准识别的双重优势,全面提升泌尿系统疾病的筛查准确率与诊断效能,能全面反映尿液理化性质与有形成分异常,可为临床筛查泌尿系统疾病提供可靠的检测方案。

Abstract

Objective To investigate the clinical application value of combined urine dry chemistry and urinary sediment testing in the screening of urinary system diseases, to compare the diagnostic performance of single-test versus combined-test modalities, and provide a clinical basis for rapid and accurate screening of urinary system disorders. Methods A retrospective study was conducted involving 200 patients with suspected urinary system diseases admitted to the nephrology and urology departments of our hospital from January 2024 to June 2025. All subjects underwent both urine dry chemistry and urinary sediment testing simultaneously. The results of these tests as well as combined testing were statistically analyzed, with clinical comprehensive diagnosis and 6-month follow-up outcomes serving as gold standards to evaluate the diagnostic performance of each method. Results The combined testing demonstrated significantly higher sensitivity and accuracy compared to either single test method(P<0.05). Although the specificity of combined testing showed a slight decrease, this difference was not statistically significant(P>0.05). The consistency between urine dry chemistry and urinary sediment testing was moderate(kappa=0.58). Conclusion The integrated approach combining rapid urine dry chemistry screening with precise identification of urinary sediment components offers dual advantages in enhancing the accuracy and diagnostic efficacy of urinary system disease screening. It comprehensively reflects abnormalities in urine physicochemical properties and cellular components, it can provide a reliable detection plan for clinical screening of urinary system diseases.

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[1]兰茜,黄欢.尿干化学与尿沉渣联合检测在泌尿系统疾病筛查中的临床价值分析[J].疾病预防与控制,2026,2(06):193-196.