ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-05-042 检验与方法 2026, 2(05): 165-168

超声检查在胎儿先天性心脏病筛查中的应用效果观察

浙江大学医学院附属第四医院

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摘要

目的 探讨超声技术在胎儿先天性心脏病筛查中的实际效能。方法 选取接受常规产前检查的妊娠妇女80例作为研究对象,于妊娠特定阶段实施系统性超声扫查,重点观察胎儿四腔心切面、左右心室流出道、三血管气管切面等多切面解剖结构。应用彩色多普勒血流显像技术评估心脏血流动力学状态。所有影像学资料由两位经验丰富的高年资超声科医师进行双盲判读。以分娩后新生儿心脏超声评估或引产后病理解剖结果为参照标准,计算产前超声诊断敏感度、特异度、阳性预测值及阴性预测值。结果 在80例研究对象中,产前超声共筛查出32例结构性心脏发育异常。经产后验证,诊断真阳性病例29例,假阳性3例,假阴性3例,真阴性45例。数据显示,该方法筛查胎儿先天性心血管畸形的敏感度为90.63%(29/32),特异度为93.75%(45/48),阳性预测值与阴性预测值分别为90.63%(29/32)和93.75%(45/48)。结论 规范化多切面超声扫查结合血流动力学评估,可作为胎儿先天性心血管结构异常的有效筛查工具。该方法具有较高诊断准确性,对提升产前诊断能力、指导临床干预策略优化具备实际应用价值。

Abstract

Objective To investigate the actual efficacy of ultrasound technology in screening for fetal congenital heart disease. Methods A total of 80 pregnant women undergoing routine prenatal examination were selected as subjects. Systematic ultrasound scanning was performed at specific gestational stages, focusing on the anatomical structures of multiple sections including the fetal four-chamber view, left and right ventricular outflow tracts, and three-vessel trachea view. Color doppler flow imaging was used to evaluate cardiac hemodynamic status. All imaging data were interpreted in a double-blind manner by two experienced senior ultrasound physicians. Taking neonatal cardiac ultrasound assessment after delivery or pathological anatomy results after induction of labor as the reference standard, the sensitivity, specificity, positive predictive value and negative predictive value of prenatal ultrasound diagnosis were calculated. Results Among the 80 subjects, 32 cases of structural cardiac dysplasia were detected by prenatal ultrasound. After postpartum verification, there were 29 true positive cases, 3 false positive cases, 3 false negative cases and 45 true negative cases. The data showed that the sensitivity of this method for screening fetal congenital cardiovascular malformations was 90.63%(29/32), the specificity was 93.75%(45/48), and the positive predictive value and negative predictive value reached 90.63%(29/32) and 93.75%(45/48), respectively. Conclusion Standardized multi-section ultrasound scanning combined with hemodynamic evaluation can be used as an effective screening tool for fetal congenital cardiovascular structural abnormalities. This method has high diagnostic accuracy and practical application value for improving prenatal diagnosis ability and guiding the optimization of clinical intervention strategies.

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[1]李焕.超声检查在胎儿先天性心脏病筛查中的应用效果观察[J].疾病预防与控制,2026,2(05):165-168.