垂体后叶素联合缩宫素对子宫肌瘤剔除术患者循环系统、止血效果的影响

Objective To analyze the effect of combining posterior pituitary hormone and oxytocin in the operation of myomectomy. Methods A total of 60 patients who underwent laparoscopic myomectomy in our hospital from October 2022 to October 2025 were retrospectively included. Among them, 32 patients who used oxytocin alone during the operation were included in the control group, and 28 patients who used both posterior pituitary hormone and oxytocin were included in the research group. The surgical-related indicators, circulatory system indicators [mean arterial pressure(MAP), heart rate(HR)], hemostasis effect, and complication rate were compared between the two groups. Results There was no significant difference in the time to first defecation and hospital stay after surgery between the research group and the control group(P>0.05). The intraoperative blood loss in the research group was less than that in the control group, and the operation time was shorter(P<0.05). The research group had higher MAP levels than the control group at 10 minutes(T2) and 30 minutes(T3) after administration, and at the end of the surgery(T4), while their HR levels were lower than those of the control group(P<0.05). The hemoglobin and red blood cell count at 24 hours after surgery in the research group were higher than those in the control group(P<0.05). The complication rate in the research group was significantly lower than that in the control group(P<0.05). Conclusion The combined use of posterior pituitary hormone and oxytocin in uterine fibroids removal surgery can improve the hemostasis effect, effectively protect the patient's circulatory system, shorten the operation time, and reduce the complication rate.