首发缺血性脑卒中患者卒中后认知功能障碍现状及影响因素研究

Objective To investigate the current status of cognitive function in patients with first-episode ischemic stroke and analyze its influencing factors, so as to provide a reference for clinical intervention strategies. Methods By using the convenience sampling method, 165 patients with the first episode of ischemic stroke who were hospitalized in two tertiary grade A general hospitals, namely the Affiliated Zhongda Hospital of Southeast University and Jiangsu Provincial People's Hospital, from August 2023 to March 2024 were selected as the survey subjects. The general information questionnaire and the Montreal Cognitive Assessment Scale were used for the investigation. Results A total of 165 questionnaires were distributed, and 153 valid questionnaires were recovered, yielding an effective response rate of 92.7%(153/165). The median cognitive function score(interquartile range) for the 153 patients was 24(20, 26) points. Among them, 71.9%(110/153) of the patients with first-episode ischemic stroke were found to have cognitive impairment. Multiple linear regression analysis revealed that female gender, advanced age, hyperlipidemia, and multiple lesion sites were risk factors for cognitive impairment in these patients. Conclusion Post-Stroke Cognitive Impairment is highly prevalent among patients with first-episode ischemic stroke, particularly in female patients, those of advanced age, those with hyperlipidemia, and those with multiple lesion sites. Proactive prevention, early identification, and intervention for cognitive dysfunction are crucial to reduce the incidence of post-stroke cognitive impairment in this patient population and improve their quality of life.