冠状动脉CT血管成像评估冠心病合并新冠感染痰瘀证不同证型脂质斑块特征

Objective To explore the correlation between lipid plaque distribution characteristics obtained from coronary computed tomography angiography(CTA) and different Traditional Chinese Medicine(TCM) syndromes in patients with coronary heart disease complicated by COVID-19 infection. Methods A total of 53 patients with coronary heart disease and COVID-19 infection who underwent coronary CT angiography in the cardiology department of our hospital from January 2023 to December 2024 were enrolled as the study subjects, diagnosed with TCM syndromes of phlegm, stasis, or phlegm-stasis intermingled. Medical records, TCM diagnostic data, and coronary CT angiography results were collected and analyzed using statistical software. Results In terms of soft plaque quantity, the phlegm-stasis intermingled group exhibited significantly higher mean values than the non-phlegm-stasis intermingled group(P<0.05). For calcified plaque quantity, the phlegm-stasis intermingled group showed significantly lower mean values than the nonphlegm-stasis intermingled group(P<0.05). There was a statistically significant difference in the degree of coronary stenosis between the phlegm-stasis intermingled group and the non-phlegm-stasis intermingled group(P<0.05). The plaque size indices(length/load/volume) and component indices(calcification/lipid/fiber) of patients in phlegm-stasis intermingled group were significantly higher than those of non-phlegm-stasis intermingled group, and the difference was statistically significant(P<0.05). Conclusion Coronary CTA examination for patients with coronary heart disease complicated by COVID-19 phlegm-stasis syndrome helps assess the degree of coronary stenosis, accurately determine plaque characteristics and quantity, and quantify plaque features, thereby providing data support for clinical diagnosis and treatment.