ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-03-042 检验与方法 2026, 2(03): 165-168

基于消化道症状群的干预在肺癌术后化疗的效果

广东药科大学附属第一医院

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摘要

目的 探讨基于消化道症状群的干预模式应用于肺癌术后化疗患者的效果。方法 选取我院2023年2月至2025年2月间收治的105例肺癌术后化疗患者,随机分为两组。对照组53例患者进行常规肺癌化疗护理,观察组52例患者给予基于消化道症状群的干预模式,两组患者均连续干预三个化疗周期。比较两组患者干预前后消化道症状群严重程度[安德森胃肠道肿瘤症状汉化版量表(MDASI)]、营养指标[白蛋白(Alb)、前白蛋白(PAB)、总蛋白(TP)]、心理状态[心理痛苦温度计(DT)]、生活质量[中文版肺癌患者生活质量量表(EORTC QLQ-LC43)]。结果 两组患者干预前各项指标相比不存在显著性差异(P>0.05),两组患者干预后均有改善。与对照组相比,观察组患者干预后MDASI评分、DT评分、EORTC QLQ-LC43症状维度评分较低,Alb、PAB、TP水平和EORTC QLQ-LC43功能维度水平较高(P<0.05)。结论 肺癌术后化疗患者应用基于消化道症状群的干预模式效果良好,可有效减轻患者消化道症状群严重程度及对生活的影响,提升患者营养状态,并改善患者心理状态及生活质量。

Abstract

Objective To explore the effect of a digestive tract symptom cluster-based intervention model in lung cancer patients undergoing postoperative chemotherapy. Methods A total of 105 eligible patients(from February 2023 to February 2025) were randomly divided into control group(53 cases, conventional chemotherapy nursing) and observation group(52 cases, symptom cluster-based intervention), with interventions lasting three chemotherapy cycles. Indicators including gastrointestinal symptom severity(Chinese MDASI), nutritional status(Alb, PAB, TP), psychological state(DT), and quality of life(Chinese EORTC QLQ-LC43) were compared pre-and post-intervention. Results No significant intergroup differences were observed in baseline indicators(P>0.05), with both groups improving post-intervention. Compared with the control group, the observation group had lower MDASI, DT and EORTC QLQ-LC43 symptom scores, as well as higher Alb, PAB, TP levels and EORTC QLQ-LC43 functional dimension scores(P<0.05). Conclusion The digestive tract symptom cluster-based intervention is effective for lung cancer patients undergoing postoperative chemotherapy, as it reduces gastrointestinal symptom severity, improves nutritional status, and enhances psychological well-being and quality of life.

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[1]陈海媚.基于消化道症状群的干预在肺癌术后化疗的效果[J].疾病预防与控制,2026,2(03):165-168.