ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-03-036 临床药物与手术治疗 2026, 2(03): 141-144

维生素D、钙剂联合抗阻训练对老年骨质疏松合并肌少症的影响

北京积水潭医院贵州医院

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摘要

目的 分析维生素D、钙剂联合抗阻训练对老年骨质疏松合并肌少症的影响。方法 选取2024年1月-2025年12月我院收治的100例老年骨质疏松合并肌少症患者,按照不同治疗方式分为两组,对比维生素D、钙剂治疗(对照组,n=50)与维生素D、钙剂联合抗阻训练治疗(观察组,n=50)的临床效果。结果 观察组治疗后总有效率、骨密度、骨钙素均高于对照组,Ⅰ型原胶原N端前肽(P1NP)、β胶原降解产物(β-CTX)、碱性磷酸酶低于对照组(P<0.05);观察组治疗后视觉模拟评分(VAS)、奥斯维兹功能障碍指数(ODI)低于对照组(P<0.05);观察组治疗后生活质量评分高于对照组(P<0.05)。结论 老年骨质疏松合并肌少症患者采取维生素D、钙剂联合抗阻训练干预,可以有效改善患者骨代谢,增加骨密度,提升患者活动能力和生活质量。

Abstract

Objective To analyze the effects of vitamin D, calcium supplements combined with resistance training on elderly osteoporosis complicated with sarcopenia. Methods 100 elderly patients with osteoporosis complicated with sarcopenia admitted to our hospital from January 2024 to December 2025 were selected and divided into two groups according to different treatment methods. The clinical effects of vitamin D, calcium supplements treatment(control group, n=50) and vitamin D, calcium supplements combined with resistance training treatment(observation group, n=50) were compared. Results The total effective rate, bone density, and osteocalcin in the observation group after treatment were higher than those in the control group, while procollagen type I N-terminal propeptide(P1 NP), beta-C-terminal telopeptide(β-CTX), and alkaline phosphatase were lower than those in the control group(P<0.05), the Visual Analogue Scale(VAS) score and Oswestry Disability Index(ODI) score of the observation group after treatment were lower than those of the control group(P<0.05), the quality of life score of the observation group after treatment was higher than that of the control group(P<0.05). Conclusion For elderly patients with osteoporosis complicated with sarcopenia, taking vitamin D, calcium supplements combined with resistance training intervention can effectively improve the bone metabolism, increase bone density, enhance the activity ability and quality of life of patients.

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[1]陈楷,宋斌,邹光文.维生素D、钙剂联合抗阻训练对老年骨质疏松合并肌少症的影响[J].疾病预防与控制,2026,2(03):141-144.