ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-03-029 临床药物与手术治疗 2026, 2(03): 113-116

髓内钉内固定技术在四肢长管骨创伤骨折治疗中的应用价值分析

金沙县人民医院

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摘要

目的 以四肢长管骨创伤骨折患者作为观察对象,以髓内钉内固定技术作为治疗方法,就观察对象采用上述治疗方法的临床效果进行分析和探讨。方法 将2023年1月至2023年6月期间入院的患者分为对照组,该组的患者例数为47例,该组患者采用钢板内固定技术治疗;2023年7月至2023年12月期间入院的患者分为观察组,该组的患者例数为47例,其为髓内钉内固定技术治疗。对比两组的手术指标、治疗前后的炎症反应、骨代谢指标及并发症发生率等指标。结果 与对照组相比,观察组术中出血量更少(P<0.05);与对照组相比,在手术时间、下床活动时间、住院时间等指标方面,观察组更短(P<0.05);治疗后,与对照组相比,观察组白细胞介素-6(IL-6)、降钙素原(PCT)、C反应蛋白(CRP)的水平更低(P<0.05);治疗后,与对照组相比,观察组β-胶原降解产物(β-CTX)、总1型胶原氨基酸延长肽(t-PINP)指标较低,而血清25-羟维生素D(25-OH-VD)更高(P<0.05);在对比并发症发生率时,可以发现观察组的数值相较于对照组呈现出较低的趋势(P<0.05)。结论 对于四肢长管骨创伤骨折患者而言,采用髓内钉内固定技术治疗可获得较为理想的治疗效果,不仅可以有效减少其术中出血量,缩短其手术时间和术后恢复时间,还可以减轻其炎症反应,改善其骨代谢水平,降低并发症的发生风险。

Abstract

Objective To take patients with long bone trauma fractures of the limbs as the observation subjects and intramedullary nail internal fixation as the treatment method, and to analyze and discuss the clinical effect of the above treatment method on the observation subjects. Methods Patients admitted to the hospital from January 2023 to June 2023 were assigned to the control group, with a total of 47 patients in this group. The treatment method for these patients was internal fixation with plates. Patients admitted to the hospital from July 2023 to December 2023 were assigned to the observation group, with a total of 47 patients in this group. The treatment method was internal fixation with intramedullary nails. Compared the surgical indicators, inflammatory responses before and after treatment, bone metabolism indicators, and the incidence of complications among the two groups. Results Compared with the control group, the intraoperative blood loss in the observation group was lower(P<0.05). Compared with the control group, the observation group had shorter durations in terms of operation time, time to get out of bed, and hospital stay(P<0.05). After treatment, compared with the control group, the levels of interleukin-6(IL-6), procalcitonin(PCT), and C-reactive protein(CRP) in the observation group were lower(P<0.05). After treatment, compared with the control group, the observation group had relatively lower levels of indicators such as β-collagen degradation product(β-CTX) and total type 1 collagen amino acid elongation peptide(t-PINP), and in the comparison of serum 25-hydroxyvitamin D(25-OH-VD), the observation group was relatively higher compared to the control group(P<0.05). When comparing the incidence of complications, it could be found that the values of the observation group showed a lower trend compared to the control group(P<0.05). Conclusion For patients with fractures of long bones in the limbs, the use of intramedullary nail internal fixation technology can achieve a relatively ideal therapeutic effect. It not only effectively reduces the intraoperative blood loss, shortens the operation time and postoperative recovery time, but also alleviates the inflammatory response, improves the bone metabolism level, and reduces the risk of complications.

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[1]孟扬声.髓内钉内固定技术在四肢长管骨创伤骨折治疗中的应用价值分析[J].疾病预防与控制,2026,2(03):113-116.