ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2026-02-050 检验与方法 2026, 2(02): 197-200

夫精宫腔内人工授精助孕影响因素分析

蚌埠市第三人民医院

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摘要

目的 分析夫精宫腔内人工授精妊娠率影响因素。方法 收集2024年1月至2025年5月期间在蚌埠市第三人民医院生殖中心行夫精宫腔内人工授精的不孕夫妇的临床资料,对夫精宫腔内人工授精妊娠率影响因素进行多元Logistic回归分析。结果 44对不孕症夫妻临床妊娠率为17.65%,未妊娠组与妊娠组女方年龄、抗苗勒管激素(AMH)、精液优化前后前向精子数、周期次数、授精次数差异有统计学意义,单因素Logistic回归分析显示,女方年龄、AMH、精液优化前后前向精子数、双次授精及周期次数与妊娠结局相关。受试者工作特征曲线(ROC)分析显示前向预测妊娠成功的曲线下面积(AUC)为0.911。结论 精液优化后前向精子数是临床妊娠率的独立影响因素。

Abstract

Objective To analyze the factors affecting the pregnancy rate of intrauterine artificial insemination with husband's sperm. Methods Clinical data of infertile couples who underwent intrauterine insemination with husband's sperm at the Reproductive Center of the Third People's Hospital of Bengbu City from January 2024 to May 2025 were collected, and multiple Logistic regression analysis was conducted on the factors affecting the pregnancy rate of intrauterine artificial insemination with husband's sperm. Results The clinical pregnancy rate of 44 infertile couples was 17.65%. There were statistically significant differences in female age, anti mullerian hormone(AMH), forward sperm count before and after semen optimization, cycle count, and fertilization count between the non pregnant and pregnant groups. Univariate Logistic regression analysis showed that female age, AMH, the number of forward sperm before and after semen optimization, double insemination, and number of cycles were all related to the pregnancy outcomes. Receiver operating characteristic curve(ROC) analysis showed that the area under the curve(AUC) for predicting successful pregnancy forward was 0.911. Conclusion The forward sperm count after semen optimization is an independent influencing factor on clinical pregnancy rate.

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[1]许颖,徐鹏琛.夫精宫腔内人工授精助孕影响因素分析[J].疾病预防与控制,2026,2(02):197-200.