疾控中心微生物实验室质量控制的影响因素及对策研究

Abstract: Objective To explore the main influencing factors of quality control in the microbiological laboratory of the Center for Disease Control and Prevention and propose targeted improvement measures. Methods 300 test samples from the microbiological laboratory of the Center for Disease Control and Prevention from January 2021 to December 2022 were selected as the research objects, and divided into two groups according to the implementation time of quality control measures. Among them, 150 samples from January to December 2021 were the pre-implementation group and 150 samples from January to December 2022 were the post-implementation group. The occurrence of quality problems in the two groups was statistically analyzed to identify the key factors affecting laboratory quality control and compare the differences in the effects before and after the implementation of quality control measures. Results The incidence of quality problems in the post-implementation group was 4.00%, significantly lower than 22.00% in the pre-implementation group, with a statistically significant difference (P＜0.05). Among the quality problems, sample factors accounted for 23.08%, operational factors accounted for 28.21%, personnel factors accounted for 25.64%, instrument factors accounted for 10.26% and environmental factors accounted for 12.82%. After the implementation of quality control measures, the quality problems caused by samples, instruments, and the environment were significantly controlled (P＜0.05). Conclusion The quality control in the microbiological laboratory of the Center for Disease Control and Prevention is influenced by multiple factors such as samples, operations, personnel, instruments, and the environment. By implementing targeted quality control measures, the incidence of quality problems can be effectively reduced and the accuracy of test results can be improved.