高血压冠心病患者低密度脂蛋白和肌钙蛋白Ⅰ水平及意义

Objective To analyze the expression and clinical significance of low-density lipoprotein(LDL) and troponin Ⅰ(cTnⅠ) in patients with hypertension combined with coronary heart disease(CHD). Methods 126 hypertensive patients admitted to our hospital from May 2023 to June 2024 were selected as the subjects of this experiment. Based on the results of coronary angiography, they were divided into combined CHD group(n = 58) and non-CHD group(n = 68). The basic data, LDL and cTnⅠ levels of the two groups were analyzed. Univariate and Logistic multifactorial analyses were performed to analyze the independent factors affecting hypertension patients with comorbid CHD. Results The results of the univariate analysis showed that there were significant differences between the two groups in terms of smoking status, cTnⅠ and LDL(P<0.05). The multivariate analysis of the Logistic regression model indicated that smoking status(P = 0.007, OR = 5.100), cTnⅠ(P = 0.013, OR = 6.110) and LDL(P = 0.002, OR = 4.518) levels were independent influencing factors for the concurrent CHD in hypertensive patients. Conclusion Compared with patients with hypertension alone, cTnⅠ and LDL levels were higher in patients with hypertension combined with CHD. Smoking, cTnⅠ and LDL levels are independent factors affecting CHD in hypertensive patients, and these factors should be controlled in clinical practice to effectively reduce the risk of CHD in hypertensive patients.