ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2025-05-075 心脑血管疾病与治疗 2025, 1(05): 49-52

预后营养指数联合Grace评分评估急性非ST段抬高型心肌梗死的价值

佛山市第二人民医院

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摘要

目的 探讨预后营养指数(PNI)联合Grace评分评估急性非ST段抬高型心肌梗死的价值。方法 选择2023年9月至2024年1月我院拟接受治疗的急性非ST段抬高型心肌梗死患者100例为研究对象。根据患者入院时的Grace评分,将患者分为高危组42例和非高危组58例。检测患者的射血分数(EF)、N末端B型利钠肽前体(NT-pro BNP)、肌钙蛋白I(cTnI)水平。观察两组EF、NT-pro BNP、cTnI水平、Logistic回归分析、预后营养指数联合Grace评分与急性非ST段抬高型心肌梗死患者的相关性。结果 高危组EF高于非高危组,NTpro BNP、肌钙蛋白I水平低于非高危组,统计学结果有显著差异(P<0.05)。以急性非ST段抬高型心肌梗死为因变量,进行相关性分析,结果显示,EF与病情呈正相关(r=0.709,P<0.05),NT-pro BNP、肌钙蛋白I水平与病情呈负相关(r=-0.673、-0.715,P<0.05)。结论 预后营养指数联合Grace评分评估急性非ST段抬高型心肌梗死的价值较高,可根据机体EF、NT-pro BNP、肌钙蛋白I水平辅助临床诊治。

Abstract

Objective To explore the value of prognostic nutritional index combined with Grace score in evaluating acute non-ST-segment elevation myocardial infarction. Methods A total of 100 patients with acute non-ST-segment elevation myocardial infarction(NSTEMI) who were planned to be admitted to our hospital from September 2023 to January 2024 were selected as the research subjects. According to the Grace score of the patients at admission, the patients were divided into a high-risk group of 42 cases and a non-high-risk group of 58 cases. The ejection fraction(EF), N-terminal pro-B-type natriuretic peptide(NT-pro BNP) level, and cardiac troponin I(cTnI) level were measured for all patients. The levels of EF, NT-pro BNP, troponin I were observed in the two groups. Logistic regression analysis and the correlations between prognostic nutritional index combined with Grace score and patients with acute NSTEMI were explored. Results The EF in the high-risk group was higher than that in the non-high-risk group, while the levels of NT-pro BNP and troponin I were lower than those in the non-high-risk group. The statistical results showed significant differences(P<0.05). Taking acute NSTEMI as the dependent variable, a correlation analysis was conducted. The results showed that EF was positively correlated with the condition(r = 0.709, P<0.05), while the levels of NT-pro BNP and cTnI were negatively correlated with the condition(r =-0.673,-0.715, P<0.05). Conclusion The prognostic nutritional index combined with Grace score has a relatively high value in evaluating acute NSTEMI. It can assist in clinical diagnosis and treatment based on the levels of EF, NT-pro BNP and troponin I in the body.

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[1]万小亮,李兆康,李芳玲.预后营养指数联合Grace评分评估急性非ST段抬高型心肌梗死的价值[J].疾病预防与控制,2025,1(05):49-52.