ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2025-04-046 预防医学研究 2025, (04)

乙型病毒性肝炎防控中乙肝疫苗接种的实施价值评估

贵阳市第三人民医院

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摘要

目的 探究乙型病毒性肝炎防控期间,采取乙肝疫苗接种方案的有效性。方法 将 2020 年 1 月至 2021年 1 月完成三针乙肝疫苗接种的人群作为观察对象,共 100 名。在接种后第 1 年、第 2 年和第 3 年开展乙肝抗体滴度检测工作。记录各组乙肝抗体滴度,目标人群首次接种乙肝疫苗后表面抗体转阳结果。结果 在乙肝抗体滴度方面,目标人群接种后第 1 年比接种后第 2 年、第 3 年的数据高(P<0.05);100 名目标人群接种后第 1 年乙肝病毒表面抗体阳性率高于接种第 2 年、第 3 年(P<0.05);接种乙肝疫苗 24 周后的目标人群乙肝表面抗体转阳率最高(P<0.05)。结论 乙型病毒性肝炎防控过程中,采取乙肝疫苗接种对策,对预防乙型病毒性肝炎的发生具有重要价值,并且能够维护人们的健康。

Abstract

Objective To explore the effectiveness of hepatitis B vaccination program during the prevention and control of hepatitis B virus. Methods A total of 100 people who completed three doses of hepatitis B vaccination from January 2020 to January 2021 were selected as the observation targets. Hepatitis B antibody titers were tested in the first, second and third years after vaccination. The titer of hepatitis B antibody in each group and the results of surface antibody conversion after the first vaccination of hepatitis B vaccine in the target population were recorded. Results In terms of hepatitis B antibody titer, the first year after vaccination was higher than the second and third years after vaccination in the target population (P<0.05). The positive rate of hepatitis B surface antibody in the 100 target population in the first year after vaccination was higher than that in the second and third years after vaccination (P<0.05). The positive rate of hepatitis B surface antibody was the highest in the target population after 24 weeks of hepatitis B vaccination (P<0.05). Conclusion In the process of prevention and control of hepatitis B virus, hepatitis B vaccination is of great value in preventing the occurrence of hepatitis B and maintaining people’ s health.

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[1]刘莉萍.乙型病毒性肝炎防控中乙肝疫苗接种的实施价值评估[J],2025,01(04):.