ISSN 2097-5724 CN 61-1535/R 主管·主办:陕西省疾病预防控制中心
疾病预防与控制 Disease Prevention and Control 医学学术期刊 双月刊
2025-04-013 中医学研究 2025, 1(04): 195-198

知柏地黄汤治疗2型糖尿病合并肺结核的影响分析

济宁市任城区疾病预防控制中心

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摘要

目的 探讨知柏地黄汤联合二甲双胍及格列美脲治疗2型糖尿病(T2DM)合并肺结核(TB)对血糖控制和胰岛素抵抗的影响。方法 选取2023年10月至2024年10月本院收治的162例T2DM合并TB患者,按照随机数表法分为两组,每组81例。对照组采用二甲双胍联合格列美脲治疗,观察组则在对照组基础上联合知柏地黄汤治疗。对比两组疗效。结果 治疗后,观察组症状消失时间短于对照组(P<0.05)。治疗后,观察组血糖水平低于对照组(P<0.05)。此外,观察组胰岛功能优于对照组(P<0.05)。结论 知柏地黄汤联合二甲双胍及格列美脲治疗T2DM合并TB,能够有效缩短症状消失时间,降低血糖水平,并改善胰岛功能,优于单纯西药联合治疗。

Abstract

Objective To investigate the effect of Zhibai Dihuang Decoction combined with metformin and glimepiride in the treatment of type 2 diabetes mellitus(T2 DM) with pulmonary tuberculosis(TB) on blood glucose control and insulin resistance. Methods A total of 162 patients with T2 DM and TB admitted to our hospital from October 2023 to October 2024 were enrolled and divided into two groups by random number table method, with 81 patients in each group. The control group was treated with metformin combined with glimepiride, while the observation group was treated with Zhibai Dihuang Decoction in addition to the control group. Compared the therapeutic effects of two groups. Results After treatment, the disappearance time of symptoms in the observation group was shorter than that in the control group(P<0.05). Meanwhile, the blood glucose levels in the observation group were lower than those in the control group(P<0.05). In addition, the pancreatic function of the observation group was better than that of the control group(P<0.05). Conclusion The combination of Zhibai Dihuang Decoction with metformin and glimepiride in the treatment of T2 DM complicated with TB can effectively shorten the symptom time, lower blood glucose levels, and improve islet function, which is superior to the combination therapy of western medicine alone.

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[1]汪娜娜,魏霞.知柏地黄汤治疗2型糖尿病合并肺结核的影响分析[J].疾病预防与控制,2025,1(04):195-198.